Actorise 200 mcg Injection | 0.4 ml in 1 prefilled syringe

Introduction of Actorise 200 mcg Injection

Actorise 200 mcg Injection is an erythropoiesis-stimulating agent. Actorise 200 mcg Injection is used in the treatment of anaemia due to chronic kidney disease and anemia due to chemotherapy. Actorise 200 mcg Injection works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

Actorise 200 mcg Injection may cause some common adverse effects, including low blood pressure, cough, trouble breathing, stomach pain, and swelling in your arms or legs. However, Actorise 200 mcg Injection may also lead to more severe side effects, such as headache, unusual weakness or tiredness, seizure (convulsions), shortness of breath, swelling, and rapid weight gain. Please inform your doctor as these are the most frequently reported side effects. Your doctor may be able to provide suggestions for reducing or preventing these side effects.

Using Actorise 200 mcg Injection may increase the chance of severe heart or circulation issues, such as stroke or heart attack, which can be life-threatening. if you notice any symptoms such as chest pain, shortness of breath, sudden numbness or weakness, confusion, vision or balance problems, difficulty speaking or understanding, or pain or coldness in an arm or leg, you should discontinue the use of Actorise 200 mcg Injection and seek immediate medical attention from a doctor.

Before taking Actorise 200 mcg Injection, you should inform your doctor of any pre-existing medical conditions, such as uncontrolled blood pressure, heart disease, liver or kidney problems, seizures, blood clots problems or if you are currently taking any other medications, including prescription drugs, over-the-counter medications, vitamins, and herbal remedies. This is because Actorise 200 mcg Injection may interact with other medications and result in adverse effects. Your doctor may need to adjust your dosage or closely monitor you for any side effects.

Actorise 200 mcg Injection can be administered under the skin or infusion into a vein. Your doctor will decide the appropriate dose and frequency of administration based on the severity of your condition, which may change over time. It is important to follow your doctor's instructions for taking Actorise 200 mcg, as taking the wrong dose or taking too much may result in severe adverse effects. Even though it may take several weeks or months to observe the benefits of the Actorise 200 mcg Injection, you may need to undergo frequent medical tests to ensure that the medication is not causing any harmful effects.

Uses of Actorise 200 mcg Injection

Treatment of Anemia due to chronic kidney disease: Actorise 200 mcg Injection is used in the treatment of anaemia associated with chronic kidney failure in adults and paediatric patients.

Treatment of Anemia due to cancer chemotherapy: Actorise 200 mcg Injection is used in the treatment of anaemia in adult cancer patients with non-myeloid malignancies receiving chemotherapy.

Benefits of Actorise 200 mcg Injection

In Treatment of Anemia due to chronic kidney disease: Anemia caused by chronic kidney disease (CKD) is a common condition that occurs when the kidneys fail to produce enough erythropoietin (EPO), a hormone that stimulates the production of red blood cells in the bone marrow. As a result, the body may not have enough red blood cells to carry oxygen to the organs and tissues, leading to symptoms such as fatigue, weakness, shortness of breath, and dizziness. Actorise 200 mcg Injection may help the body produce more red blood cells. Iron supplements may also be recommended to support the production of healthy red blood cells. In addition, maintaining lifestyle changes such as a healthy diet, regular exercise, and quitting smoking may also be recommended to manage anaemia caused by CKD. Close monitoring of kidney function and regular blood tests are also essential in managing anaemia and preventing complications associated with CKD.

In Treatment of Anemia due to cancer chemotherapy: Anemia caused by cancer chemotherapy is a common side effect of cancer treatment that occurs when the chemotherapy drugs damage or destroy the bone marrow cells responsible for producing red blood cells. This can lead to a decrease in the number of red blood cells, resulting in symptoms such as fatigue, weakness, shortness of breath, and dizziness. Actorise 200 mcg Injection may help the body produce more red blood cells. Iron supplements may also be recommended to support the production of healthy red blood cells. In addition, maintaining lifestyle changes such as a healthy diet, regular exercise, and quitting smoking may also be recommended to manage anaemia caused by chemotherapy. Close monitoring of vitals and regular blood tests are also essential in managing anaemia and preventing complications associated with chemotherapy.

Side Effects of Actorise 200 mcg Injection

​​​​Like all medications, Actorise 200 mcg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​

Most Common Side Effects of Actorise 200 mcg Injection

• Cough
  
• Peripheral edema
• Procedural hypotension (low blood pressure)
• Convulsion
• Thromboembolism

Common Side Effects of Actorise 200 mcg Injection

• High blood pressure
  
• Rash
• Injection site pain, swelling
• Breathlessness

How to Use Actorise 200 mcg Injection?

​​Actorise 200 mcg Injection can be administered under the skin or infusion into a vein. Your doctor will decide the appropriate dose and frequency of administration based on the severity of your condition, which may change over time. It is important to follow your doctor's instructions for taking Actorise 200 mcg Injection, as taking the wrong dose or taking too much may result in severe adverse effects. Even though it may take several weeks or months to observe the benefits of the Actorise 200 mcg Injection, you may need to undergo frequent medical tests to ensure that the medication is not causing any harmful effects.​

How Actorise 200 mcg Injection Works?

​Actorise 200 mcg Injection is enough erythropoietin (EPO), a hormone that stimulates the production of red blood cells in the bone marrow. As a result, the body may not have enough red blood cells to carry oxygen to the organs and tissues, leading to symptoms such as fatigue, weakness, shortness of breath, and dizziness. Actorise 200 mcg Injection may help the body produce more red blood cells. Iron supplements may also be recommended to support the production of healthy red blood cells.​

Safety Advices Actorise 200 mcg Injection

Liver

Use with Caution

Kidney

Safe

Driving

Safe

Alcohol

Unsafe

Pregnancy

Unsafe

Breastfeeding

Unsafe

References

1. Darbepoetin Alfa, Drugs.com, Avaliable Form 

2. Aranesp 100 Micrograms Solution For Injection In Pre-filled Syringe, Amgen Europe B.v, Product Leaflet 

3. Aranesp, (darbepoetin Alfa) Injection, For Intravenous Or Subcutaneous Use,amgen Manufacturing Limited, Product Monograph 

4. Aranesp- Darbepoetin Alfa Injection, Solution, Daily Med, Avaliable Form

5. Darbepoetin Alfa, Medscape.com, Avaliable Form