Amfosted 500 mg Injection | 500 mg in 1 Vial

Introduction of Amfosted 500 mg Injection

Amfosted 500 mg Injection is used to prevent severe dry mouth caused by radiation therapy to the head and neck, which affects the salivary glands. Amfosted 500 mg Injection protects the kidneys from harmful effects caused by cisplatin when administered to patients with ovarian cancer. Amfosted 500 mg Injection does not prevent all side effects of chemotherapy drugs. However, Amfosted 500 mg can help protect your body from some of the serious side effects.

Amfosted 500 mg Injection may cause some adverse effects including nausea, vomiting, flushing (warmth, redness, or tingling sensation), fever, chills, general malaise, rash, dizziness, drowsiness, sneezing, blurred vision, double vision, or pain, itching, redness, bruising, or swelling at the injection site. If any of these effects persist or bother you, please consult your doctor. To avoid dehydration, it is recommended to stay hydrated before taking this medication. Your blood pressure will be checked before and every 5 minutes during the infusion.

Amfosted 500 mg Injection is not recommended for use in you have taken any blood pressure medication within the last 24 hours. It is essential to inform your doctor if you have pre-existing heart conditions such as irregular heartbeat or heart failure, or if you are taking any medications to treat infections. Amfosted 500 mg Injection may interact with various other medicines. You should inform your doctor of all drugs, vitamins, herbals or any other medicines you are using.

Amfosted 500 mg Injection should be administered by a qualified healthcare professional in a hospital or clinic setting. Your doctor will determine the appropriate dosage and duration of therapy based on your clinical condition. It is important to complete the entire treatment course as prescribed, even if you begin to feel better before the therapy is completed. It may take several weeks or months to observe any improvement in your condition.

Uses of Amfosted 500 mg Injection

Amfosted 500 mg Injection reduces the renal toxicity of the drug in patients with advanced ovarian cancer and also reduces the incidence of moderate to severe dry mouth caused by radiation therapy in patients with head and neck cancer.

Benefits of Amfosted 500 mg Injection

Amfosted 500 mg Injection is used to minimize the harmful effects of chemotherapy and radiation therapy on the body. Amfosted 500 mg Injection protects healthy cells and tissues from the toxicity of these treatments, thereby reducing side effects and improving the health of cancer patients. In addition, Amfosted 500 mg Injection can also reduce the damage to healthy cells caused by radiation therapy, thereby improving the treatment effect. In addition, Amfosted 500 mg has the potential to improve survival in patients receiving certain cancer treatments. For those receiving radiation therapy for head and neck cancer, Amfosted 500 mg Injection have been shown to be effective in reducing dry mouth symptoms. It is important to realize that, despite the benefits, Amfosted 500 mg Injection have potential risks and side effects. Therefore, it is important to consult your doctor about the potential benefits and harms of Amfosted 500 mg before starting treatment.

Side Effects of Amfosted 500 mg Injection

​​​​​Like all medications, Amfosted 500 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Most Common Side Effects of Amfosted 500 mg Injection

• Nausea
• Hot flushes
• Vomiting
• Fever with chills
• Drowsiness
• Dizziness
• Sneezing
• Double vision
• Blurred vision
• Itching
• Redness
• Swelling
• Bruising
  

Common Side Effects of Amfosted 500 mg Injection

• Rapid breathing
• Slow heart rate
• Seizure
• Severe skin reaction
• Swelling in the throat
• Difficulty in deglutition
• Swelling of face
• Hypocalcaemia (low calcium level in blood)
• Hypotension (low blood pressure)
• Generalized weakness
• Sore throat
• Hives
  

How to Use Amfosted 500 mg Injection?

​​Amfosted 500 mg Injection is an intravenous infusion, administered by a healthcare professional or nurse in a hospital or clinic setting. The specific dosing and administration of the Amfosted 500 mg will be determined by the patient's clinical condition, age, medical history, type of cancer and other factors. It is important to note that this Amfosted 500 mg Injection should not be self-administered, and it is important to follow the instructions of the healthcare professional administering the Amfosted 500 mg Injection. Must be watched carefully.

How Amfosted 500 mg Injection Works?

Amfosted 500 mg Injection contain an active ingredient called Amifostine, which functions by scavenging free radicals and repairing DNA damage in the body. By scavenging free radicals, Amfosted 500 mg Injection helps to reduce the toxic effects of chemotherapy and radiation therapy on healthy cells and tissues. Additionally, repairing DNA damage can help to minimize the side effects of these treatments, improving treatment outcomes and the quality of life for patients. It is important to note that the decision to use Amfosted 500 mg Injection should be made in consultation with a healthcare provider, as it may not be appropriate for all patients.

Safety Advices Amfosted 500 mg Injection

Alcohol

Unsafe

Pregnancy

Unsafe

Kidney

Safe

Breastfeeding

Safe

Driving

Unsafe

Liver

Use with Caution

References

1. Ethyol,(amifostine) For Injection, MedImmune Pharma B.v., Product Lealfet 

2. Ethyol, (amifostine) For Injection, Usb Pharma B.v., Product Leaflet 

3. Ethyol Injection, Link Medical Products Pty Ltd, Product Monograph 

4. Ethyol, (amifostine), UnitedHealthcare Individual Exchange Medical Benefit Drug Policy Effective, Avaliable Form 

5. Amifostine, Drugs.com, Avaliable Form, Online 

6. Amifostine,vinmec Healthcare, Avaliable Form, Online