Decapeptyl Depot Injection | 3.75 mg in 1 Vial

Introduction of Decapeptyl Depot Injection

​Decapeptyl Depot Injection is an intravenous medication used to treat prostate cancer and endometriosis, a condition causing excessive growth of the endometrium leading to pain and irregular periods. Additionally, Decapeptyl Depot Injection is used to treat precocious puberty in children aged 2 and above.

​The Decapeptyl Depot Injection may cause side effects such as erectile dysfunction, back pain, fatigue, and sweating. If these persist or cause discomfort, it is recommended to consult a doctor. Prolonged use of this Decapeptyl Depot Injection may lead to decreased bone density and cessation of periods for up to 7-12 weeks, and patients may be advised to take vitamin D and calcium supplements.

​Decapeptyl Depot Injection should not be used during breastfeeding or pregnancy and effective contraceptives should be used to prevent pregnancy. If the menstrual cycle continues during treatment, patients should consult their doctor.

​The Decapeptyl Depot Injection is given by a qualified healthcare professional and should not be self-administered. Before using Decapeptyl Depot Injection, inform the doctor or nurse about any pre-existing medical conditions such as heart disease, seizure disorder, electrolyte imbalance, sugar, allergy, etc. The dosage and frequency will be determined by the physician based on the condition and may be adjusted as necessary. It is important to follow the doctor's instructions and not alter the dosage or frequency without medical advice. The Decapeptyl Depot Injection may take time to take effect, but it is important to continue taking it as prescribed. Inform the doctor if any serious side effects occur.​

Uses of Decapeptyl Depot Injection

Advanced Prostate Cancer: Decapeptyl Depot Injection is used for advanced prostate cancer, a stage where the cancer cells have spread beyond the prostate gland to other parts of the body.

Endometriosis: Decapeptyl Depot Injection is used in the treatment of endometriosis, a condition causing excessive growth of the endometrium leading to pain and irregular periods.

Central Precocious Puberty (CPP): Decapeptyl Depot Injection is used in the treatment of early onset puberty in children over 2 years of age, where the body matures earlier than normal. This condition is characterized by the premature development of sexual characteristics and issues with bone growth.

Benefits of Decapeptyl Depot Injection

​​​​In the treatment of endometriosis: Endometriosis is a condition where tissue such as the lining of the uterus starts to grow in other places. The main symptoms are pain in the lower abdomen or back, period pain, pain during and after sex, constipation, diarrhoea and nausea. It can also make it difficult to get pregnant. Decapeptyl Depot Injection works by stopping the lining of your womb and any endometriosis tissue from growing too quickly. This will help to relieve any symptoms you may have. This medicine must be taken regularly to be effective and you may also need other medicines or procedures to help control your endometriosis.

​​​​Treating uterine fibroids: Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Decapeptyl Depot Injection can help control the symptoms associated with uterine fibroids, such as excessive menstrual bleeding and lower back pain, and also reduce the size of existing fibroids. It works by blocking the action of the enzyme responsible for fibroid growth. As a result, they shrink and stop growing.

​​​​In the treatment of advanced prostate cancer: The prostate is a small gland about the size of a walnut that produces a fluid called seminal fluid that nourishes and carries sperm in men. The most common symptom of prostate cancer is difficulty urinating, but sometimes there are no symptoms at all. Decapeptyl Depot Injection can reduce or stop the growth of cancer cells by reducing the amount of testosterone (a natural hormone in men) in men. This will also relieve urinary problems and make it easier to pass urine.

​​​​To treat precocious puberty (early puberty): When puberty (the change of a child's body to adult structure and size) begins before the age of 8 in girls and before the age of 9 in boys, it is called precocious puberty. Decapeptyl Depot Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is only given by a doctor and should not be used unless you have it.​

Side Effects of Decapeptyl Depot Injection

​​​Like all medicines, Decapeptyl Depot Injection may cause some side effects. If you experience any of these side effects, contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​

Most Common Side Effects of Decapeptyl Depot Injection

• Hot Flushes
• Impotence
• Dry Mouth
• Improper Sleep
• Pain in the Abdomen
• Pain in Legs, and Arms
• Excessive Sweating
• Headache
• Nose bleeding
• Bone and Muscle Pain
• Headache
• Impotence

Common Side Effects of Decapeptyl Depot Injection

• Blisters
• High Fever
• Breath Shortness
• Vision Disturbance
• Inability of Taste
• Chest Pain
• Swelling in Joints
• Discolouration of the Skin

How to Use Decapeptyl Depot Injection?

​Decapeptyl Depot Injection is an injection that must be delivered through an intravenous infusion by a skilled healthcare professional in a hospital or clinic setting. The individualized dosing and administration of Decapeptyl Depot Injection will be determined by the patient's medical status, age, past medical history, and other relevant factors. Do not self-administering this Decapeptyl Depot Injection and strictly follow the instructions given by the doctor.​

How Decapeptyl Depot Injection Works?

​Decapeptyl Depot Injection is a type of GnRH (gonadotropin-releasing hormone) analogue. Decapeptyl Depot Injection lowers sex hormone levels (testosterone in men, estrogen in women) by decreasing testosterone in men and stopping ovary hormone production, lowering estrogen levels.​

Safety Advices Decapeptyl Depot Injection

Alcohol

Unsafe

Pregnancy

Unsafe

Breastfeeding

Unsafe

Driving

Unsafe

Kidney

Use with Caution

Liver

Use with Caution

References

1. Decapeptyl 6-month 22.5 Mg Powder And Solvent For Prolonged-release Suspension For Injection, Ipsen Pharma Biotech, Product Leaflet 

2. Triptorelin (as Embonate) 3.75 Mg, 11.25 Mg & 22.5 Mg Powder For Suspension, Ipsen Pty Ltd, [date Of Revision 15 December 2022], Product Leaflet 

3. Triptorelin Injection, MedlinePlus, Available Form 

4. Trelstar (triptorelin Pamoate For Injectable Suspension), Debio Rp Martigny, Switzerland, Product Leaflet 

5. Triptorelin Controlled Release Injection, Central Drugs Standard Control Organisation (CDSCO), Available Form