Zynesp 100 mcg PFS | 100 mcg in 0.5 ml PFS

Introduction of Zynesp 100 mcg Injection

Zynesp 100 mcg PFS is an erythropoiesis-stimulating agent. Zynesp 100 mcg PFS is used in the treatment of anaemia due to chronic kidney disease and anaemia due to chemotherapy. Zynesp 100 mcg PFS works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

Zynesp 100 mcg PFS may cause some common adverse effects including low blood pressure, cough, trouble breathing, stomach pain, and swelling in your arms or legs. However, Zynesp 100 mcg PFS may also lead to more severe side effects, such as headache, unusual weakness or tiredness, seizure (convulsions), shortness of breath, swelling, and rapid weight gain. Please inform your doctor as these are the most frequently reported side effects. Your doctor may be able to provide suggestions for reducing or preventing these side effects.

Using Zynesp 100 mcg PFS may increase the chance of severe heart or circulation issues, such as stroke or heart attack, which can be life-threatening. if you notice any symptoms such as chest pain, shortness of breath, sudden numbness or weakness, confusion, vision or balance problems, difficulty speaking or understanding, or pain or coldness in an arm or leg, you should discontinue the use of Zynesp 100 mcg PFS and seek immediate medical attention from a doctor.

Before taking Zynesp 100 mcg PFS, you should inform your doctor of any pre-existing medical conditions, such as uncontrolled blood pressure, heart disease, liver or kidney problems, seizures, blood clots problems or if you are currently taking any other medications, including prescription drugs, over-the-counter medications, vitamins, and herbal remedies. This is because Zynesp 100 mcg PFS may interact with other medications and result in adverse effects. Your doctor may need to adjust your dosage or closely monitor you for any side effects.

Zynesp 100 mcg PFS can be administered under the skin or infusion into a vein. Your doctor will decide the appropriate dose and frequency of administration based on the severity of your condition, which may change over time. It is important to follow your doctor's instructions for taking Zynesp 100 mcg, as taking the wrong dose or taking too much may result in severe adverse effects. Even though it may take several weeks or months to observe the benefits of the Zynesp 100 mcg PFS, you may need to undergo frequent medical tests to ensure that the medication is not causing any harmful effects.

Uses of Zynesp 100 mcg Injection

Treatment of Anemia due to chronic kidney disease: Zynesp 100 mcg PFS is used in the treatment of anaemia associated with chronic kidney failure in adults and paediatric patients.

Treatment of Anemia due to cancer chemotherapy: Zynesp 100 mcg PFS is used in the treatment of anaemia in adult cancer patients with non-myeloid malignancies receiving chemotherapy.

Benefits of Zynesp 100 mcg Injection

Treatment of Anemia due to chronic kidney disease: Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anaemia. Zynesp 100 mcg PFS can boost your levels of red blood cells and reduce the symptoms of anaemia such as tiredness and weakness. Taking this injection improves the quality of life.

Treatment of Anemia due to cancer chemotherapy: Anemia caused by cancer chemotherapy is a common side effect of cancer treatment that occurs when the chemotherapy drugs damage or destroy the bone marrow cells responsible for producing red blood cells. This can lead to a decrease in the number of red blood cells, resulting in symptoms such as fatigue, weakness, shortness of breath, and dizziness. Zynesp 100 mcg PFS may help the body produce more red blood cells. Iron supplements may also be recommended to support the production of healthy red blood cells. In addition, maintaining lifestyle changes such as a healthy diet, regular exercise, and quitting smoking may also be recommended to manage anaemia caused by chemotherapy. Close monitoring of vitals and regular blood tests are also essential in managing anaemia and preventing complications associated with chemotherapy.

Side Effects of Zynesp 100 mcg Injection

​​​Like all medications, Zynesp 100 mcg PFS can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​

Most Common Side Effects of Zynesp 100 mcg Injection

• Cough
• Peripheral edema
• Procedural hypotension (low blood pressure)
• Convulsion
• Thromboembolism
  

Common Side Effects of Zynesp 100 mcg Injection

• High blood pressure
• Rash
• Injection site pain, swelling
• Breathlessness
  

How to Use Zynesp 100 mcg Injection?

​Zynesp 100 mcg PFS can be administered under the skin or infusion into a vein. Your doctor will decide the appropriate dose and frequency of administration based on the severity of your condition, which may change over time. It is important to follow your doctor's instructions for taking Zynesp 100 mcg PFS, as taking the wrong dose or taking too much may result in severe adverse effects. Even though it may take several weeks or months to observe the benefits of the Zynesp 100 mcg PFS, you may need to undergo frequent medical tests to ensure that the medication is not causing any harmful effects.​

How Zynesp 100 mcg Injection Works?

Zynesp 100 mcg PFS is enough erythropoietin (EPO), a hormone that stimulates the production of red blood cells in the bone marrow. As a result, the body may not have enough red blood cells to carry oxygen to the organs and tissues, leading to symptoms such as fatigue, weakness, shortness of breath, and dizziness. Zynesp 100 mcg PFS may help the body produce more red blood cells. Iron supplements may also be recommended to support the production of healthy red blood cells.

Safety Advices Zynesp 100 mcg Injection

Kidney

Safe

Liver

Use with Caution

Pregnancy

Unsafe

Driving

Safe

Alcohol

Unsafe

Breastfeeding

Unsafe

References

1. Darbepoetin Alfa, Drugs.com, Avaliable Form 

2. Aranesp 100 Micrograms Solution For Injection In Pre-filled Syringe, Amgen Europe B.v, Product Leaflet 

3. Aranesp, (darbepoetin Alfa) Injection, For Intravenous Or Subcutaneous Use,amgen Manufacturing Limited, Product Monograph 

4. Aranesp- Darbepoetin Alfa Injection, Solution, Daily Med, Avaliable Form

5. Darbepoetin Alfa, Medscape.com, Avaliable Form