Jakavi 20 mg Tablet | 10 Tablets in 1 Strip

Introduction of Jakavi 20 mg Tablet

Jakavi 20 mg Tablet is a prescription medication used to treat certain types of blood disorders. Jakavi 20 mg tablet is specifically used to treat adults with certain types of myelofibrosis (a type of bone marrow disorder) and polycythemia vera (a blood disorder characterized by an overproduction of red blood cells). A blood cell count must be performed before initiating therapy with Jakavi. Jakavi 20 mg tablet is not recommended for use in patients under 12 years of age safety and efficacy are not established.

Uses of Jakavi 20 mg Tablet

Polycythemia Vera: Jakavi 20 mg tablet is used in the treatment of polycythemia vera is a rare blood disorder in which the body produces too many red blood cells. The excess red blood cells can cause the blood to become thick and sticky, making it harder to flow through the vessels. This can lead to a number of complications, including an increased risk of blood clots that can cause a heart attack or stroke.

Chronic idiopathic myelofibrosis: Jakavi 20 mg tablet is used in the treatment of chronic idiopathic myelofibrosis (also called primary myelofibrosis) is a type of bone marrow disease in which the bone marrow is replaced by scar tissue, resulting in a decrease in the production of blood cells. The scar tissue can also lead to the accumulation of excess fluid in the abdomen (ascites) and the accumulation of fat cells in the liver and spleen.

Benefits of Jakavi 20 mg Tablet

Jakavi 20 mg tablet can be effective in reducing symptoms associated with myelofibrosis, such as fatigue, enlarged spleen, and uncontrolled bleeding.

Jakavi 20 mg tablet may improve the overall quality of life and reduce the symptoms of myelofibrosis.

Jakavi has been shown to reduce bone marrow fibrosis (scarring) in those with myelofibrosis.

Jakavi 20 mg tablet prevent cancer in those with myelofibrosis and help to prevent the progression of myelofibrosis to acute myeloid leukaemia (AML).

Side Effects of Jakavi 20 mg Tablet

Like all medication, Jakavi 20 mg tablet may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​

Most Common Side Effects of Jakavi 20 mg Tablet

• Headache, dizziness
• Weight gain
• High blood pressure
• High cholesterol
• Flatulence
• Abnormal liver function tests
• Difficulty in breathing
• Constipation

Common Side Effects of Jakavi 20 mg Tablet

• Decrease in red blood cells
• Infection

How to Use Jakavi 20 mg Tablet?

Jakavi 20 mg tablet may be taken with or without food. Take it at the same time each day. Swallow the tablet whole with a full glass of water. Do not crush, chew, or open the tablet. If you forget to take a dose, make up for it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

How Jakavi 20 mg Tablet Works?

Jakavi belongs to the class of drugs known as Janus kinase inhibitors (JAK). The action of Jakavi 20 mg tablet is based on inhibiting the activity of certain proteins called JAKs, which play a role in signalling pathways that regulate the production of certain proteins in the body. By inhibiting these proteins, Jakavi may help reduce inflammation and improve symptoms in certain diseases such as myelofibrosis and polycythemia vera.

Safety Advices Jakavi 20 mg Tablet

Driving

Unsafe

Breastfeeding

Unsafe

Pregnancy

Unsafe

Alcohol

Unsafe

Kidney

Use with Caution

Liver

Use with Caution

References

1. Jakafi, (ruxolitinib) Tablets, For Oral Use, Incyte Corporation, Product Leaflet

2. Ruxolitinib 5 Mg, 10 Mg, 15 Mg And 20 Mg Tablets, Novartis Healthcare Pvt. Ltd, Product Monograph

3. Jakavi Tablets: 5 Mg, 10 Mg, 15 Mg And 20 Mg, Novartis New Zealand Limited, Product Leaflet

4. Jakavi, Novartis Pharma Ag, Basel, Switzerland, Product Leaflet