Xolair 150 mg Injection | 5 ml in 1 packet

Introduction of Xolair 150 mg Injection

Xolair 150 mg Injection is a monoclonal antibody. It is used to prevent the number of asthma attacks (sudden episodes of wheezing, shortness of breath, and trouble breathing) in adults and children 6 years of age and older with allergic asthma (asthma caused by inhaling substances such as dander, pollen, and dust mites) whose symptoms are not controlled with inhaled steroids. 

Xolair 150 mg Injection  is used to treat nasal polyps (swelling of the lining of the nose) in adults whose symptoms are not controlled with inhaled steroids. It is also used to treat chronic hives without a known cause that cannot successfully be treated with antihistamine medications such as diphenhydramine (Benadryl), cetirizine (Zyrtec), hydroxyzine (Vistaril), loratadine (Claritin) in adults and children 12 years of age and older. Xolair 150 mg is not used to treat other forms of hives or allergic conditions. Xolair 150 mg Injection works by blocking the action of a certain natural substance in the body that causes the symptoms of allergic asthma, nasal polyps, and hives.

This medicine may cause some common adverse effects including joint pain, pain (general), fatigue, dizziness, fracture, itching, dermatitis, upper abdominal pain, nasopharyngitis, headache, and ear pain. If you experience any of these side effects or appear serious, let your doctor know. There may be ways of reducing or preventing them. This medicine does not prevent a sudden asthma attack, hence always carry your emergency inhaler with you.

Before using this Xolair 150 mg, please make sure to inform your doctor. If you have heart disease, kidney or liver disease. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

Xolair 150 mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Uses of Xolair 150 mg Injection

Allergic Asthma: Xolair 150 mg Injection is used to prevent the number of asthma attacks (sudden episodes of wheezing, shortness of breath, and trouble breathing) in adults and children 6 years of age and older with allergic asthma (asthma caused by inhaling substances such as dander, pollen, and dust mites) whose symptoms are not controlled with inhaled steroids.

Chronic Rhinosinusitis With Nasal Polyps: Xolair 150 mg Injection is used to treat nasal polyps (swelling of the lining of the nose) in adults (18 years), whose symptoms are not controlled with inhaled steroids.

Chronic Idiopathic Urticaria: Xolair 150 mg Injection is used in adults and adolescents to treat chronic hives without a known cause that cannot successfully be treated with antihistamine medications.

Benefits of Xolair 150 mg Injection

Xolair 150 mg Injection is used to treat moderate to severe asthma in patients who have not responded well to other asthma medications. It is also used to treat chronic idiopathic urticaria (hives) in patients who have not responded to other treatments and also nasal polyps (swelling of the lining of the nose) in adults whose symptoms are not controlled with inhaled steroids and also used to treat nasal polyps (swelling of the lining of the nose) in adults whose symptoms are not controlled with inhaled steroids.

Allergic Asthma: Xolair 150 mg Injection is an effective treatment for allergic asthma. It works by targeting and blocking immunoglobulin E (IgE), a molecule involved in the allergic response that triggers asthma symptoms. By reducing the amount of IgE in the body, omalizumab can help prevent asthma symptoms from occurring.

Chronic Rhinosinusitis With Nasal Polyps: Xolair 150 mg Injection may help to the reduction in nasal polyp size, improve the sense of smell, and reduce the use of corticosteroid medications. The treatment may also reduce the need for surgery in some patients with chronic rhinosinusitis with nasal polyps.

Chronic Idiopathic Urticaria: Chronic idiopathic urticaria (CIU) is a condition that causes itchy, red, and swollen skin patches (hives) that can last for several weeks or months. Xolair 150 mg Injection may improve the symptoms of chronic idiopathic urticaria in patients who have not responded to other treatments.

Side Effects of Xolair 150 mg Injection

​​​​​​​​​​Like all medications, Xolair 150 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​​​​

Most Common Side Effects of Xolair 150 mg Injection

• Injection site reactions
• Itching
• Dermatitis
• Upper abdominal pain
• Inflammation of the throat and nasal passages
• Ear pain​

Common Side Effects of Xolair 150 mg Injection

• Joint pain
• Pain
• Fatigue
• Dizziness
• Fracture
  

How to Use Xolair 150 mg Injection?

​Xolair 150 mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.​

How Xolair 150 mg Injection Works?

Xolair 150 mg Injection works by binding to a protein called immunoglobulin E (IgE), which is involved in the allergic response. Binding to IgE protein Xolair 150 mg prevents it from triggering the release of histamine and other chemicals that cause inflammation and airway constriction in asthma patients, and reduces the severity and frequency of hives in patients with chronic idiopathic urticaria and nasal polyps symptoms.

Safety Advices Xolair 150 mg Injection

Alcohol

Unsafe

Driving

Unsafe

Kidney

Use with Caution

Liver

Use with Caution

Pregnancy

Safe

Breastfeeding

Safe

References

1. Xolair 150 Mg Powder Vial And Diluent For Solution For Injection, Novartis New Zealand Limited, Product Leaflet 

2. Xolair (omalizumab) For Injection, For Subcutaneous Use, Genentech, Inc, Product Leaflet

3. Xolair 75 Mg, 150 Mg Solution For Injection, Novartis Pharma Ag, Product Leaflet

4. Omalizumab Injection, Medlineplus.com, Avaliable Form

5. Xolair 150 Mg, Powder And Solvent For Solution For Injection, Novartis Pharma S.a.s, Avaliable Form