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Acotrexed 100 mg Injection
Acotrexed 100 mg Injection
Prescription Required
Prescription Required

Acotrexed 100 mg Injection | 100 mg in 1 Vial

1022.00
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Accord Pharma
Pemetrexed 100 mg
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Introduction of Acotrexed 100 mg Injection

Acotrexed 100 mg Injection is used to treat non-small cell lung cancer and malignant pleural mesothelioma.

Acotrexed 100 mg Injection is given by injection by a qualified healthcare professional. Your doctor will decide what dose is needed and how often you need to take it. This will depend on what you are being treated for and may change occasionally. It would help if you took it exactly as advised by your doctor. Taking too much or not taking it at all can cause severe side effects. It may take several weeks or months before you see or feel the benefits of this medicine but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine are nausea, vomiting, loss of appetite, and hair loss. This Acotrexed 100 Injection can reduce the number of blood cells (decrease red and white blood cells) in your blood, making you more susceptible to infection. You will need regular blood checks to monitor your blood cell counts, as well as your heart, liver, and blood uric acid levels.

Before starting this Acotrexed 100 mg Injection, it's important to tell your doctor about any pre-existing medical conditions such as heart disease, liver or kidney problems, and any ongoing treatment for infections. It's also important to tell your doctor about all the medicines you are currently taking as they may interact with this medicine. It's also not advisable to use this medicine if you are pregnant or breastfeeding. Both men and women should use effective contraception throughout treatment to prevent unwanted pregnancy.


Uses of Acotrexed 100 mg Injection

  • Non-small cell lung cancer
  • Malignant pleural mesothelioma


Benefits of Acotrexed 100 mg Injection

Non-small cell lung cancer: Non-small cell lung cancer, a major form of lung cancer, affects people regardless of their smoking status. Acotrexed 100 mg Injection is proving to be a valuable tool in the fight against this disease, either as monotherapy or in combination with other medicines. This drug has considerable potency and toxicity, which underlines the importance of discussing its potential risks and benefits with your doctor. During treatment, it's advisable to avoid alcohol and to prioritise hydration by increasing fluid intake.

In Malignant pleural mesothelioma: Malignant pleural mesothelioma is a particularly aggressive form of cancer that typically starts in the lungs and lining of the ribs. Acotrexed 100 mg Injection is used in combination with other medicines to treat this condition. Its primary function is to target and eliminate cancer cells by stopping their ability to multiply. By preventing the cancer from spreading to nearby areas, this treatment helps to control its progression. It's important to follow your doctor's instructions closely and ask for clarification if you're not sure.


Side Effects of Acotrexed 100 mg Injection

Acotrexed 100 mg Injection may cause some adverse effects which may vary from person to person. Some of these adverse effects are listed below.


Most Common Side Effects of Acotrexed 100 mg Injection

  • Fatigue
  • Nausea
  • Vomiting
  • Diarrhoea
  • Redness, swelling, or sores in the mouth
  • Loss of appetite, sensation
  • Increased skin pigmentation
  • Watery and inflamed eyes, taste change
  • Fever
  • Muscle weakness
  • Dehydration
  • Constipation
  • Skin rash
  • Hair loss


Common Side Effects of Acotrexed 100 mg Injection

  • Infection
  • Severe allergic reaction
  • Breathlessness, intense chest pain, or cough with bloody sputum
  • Decrease in white blood cell count
  • Kidney failure
  • Abnormal liver function


How to Use Acotrexed 100 mg Injection?

Acotrexed 100 mg Injection will be administered by a nurse or doctor in a clinic or hospital. It is available in an injectable form that is injected into the vein. You will need to follow the doctor's instructions to the letter during the treatment.


How Acotrexed 100 mg Injection Works?

Acotrexed 100 mg Injection works by inhibiting certain enzymes involved in the production of nucleotides, which are essential building blocks for DNA and RNA. By interfering with this process, pemetrexed inhibits the growth and replication of cancer cells.


Safety Advices Acotrexed 100 mg Injection

liver
Liver
Safe

Acotrexed 100 mg is safe to use in patients with liver disease. No dose adjustment of Acotrexed 100 Injection is recommended. If you experience any side effects please consult your doctor.

pregnancy
Pregnancy
Unsafe

Acotrexed 100 mg Injection should be avoided during pregnancy due to the clear evidence of potential harm to the developing fetus. However, in rare cases of life-threatening situations where the benefits outweigh the risks, a doctor may consider prescribing it. It's crucial to consult your doctor for personalized guidance regarding the use of Acotrexed 100 Injection during pregnancy.

breastfeeding
Breastfeeding
Use with Caution

Using Acotrexed 100 Injection while breastfeeding requires careful consideration. It's advisable to pause breastfeeding until the mother's treatment is finished and the drug has been fully cleared from her system.

alcohol
Alcohol
Unsafe

It's generally recommended to avoid consuming alcohol while undergoing treatment with Acotrexed 100 mg Injection or any other chemotherapy medication. Alcohol can interact with certain medications, potentially affecting their effectiveness or causing adverse reactions. Additionally, alcohol consumption may exacerbate some of the side effects associated with chemotherapy, such as nausea, vomiting, and liver toxicity.

driving
Driving
Unsafe

Acotrexed 100 mg Injection has potential side effects that may impair your ability to drive. Its tendency to cause drowsiness may impair your ability to drive a vehicle safely.

kidney
Kidney
Use with Caution

Caution should be exercised when considering the use of Acotrexed 100 mg in patients with renal disease. Depending on the severity of the renal condition, dose adjustments may be warranted. It is imperative to consult a physician prior to initiating this medication. In particular, the use of Acotrexed 100 mg Injection is discouraged in individuals with moderate to severe renal impairment in order to maintain treatment safety and efficacy. Always prioritise discussions with healthcare providers to tailor the treatment plan to individual medical requirements.


References

1. Pemetrexed Injection, Solution, Concentrate, Avaliable From

2. Pemetrexed-aft 100 Mg and 500 Mg Powder for Injection, Product Leaflet

3. Alimta (Pemetrexed Disodium) Injection, Powder, Lyophilized, for Solution for Intravenous Use, Product Leaflet

4. Pemetrexed for Injection, Usp, Avaliable From

5. Pemetrexed for Injection, Available From

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