Actinocin 0.5 mg Injection | 0.5 mg in 1 Vial

Introduction of Actinocin 0.5 mg Injection

Actinocin 0.5 mg Injection belongs to the class of medications called antibiotics. It is prescribed for the treatment of several types of cancer, including Ewing's sarcoma (soft tissue sarcoma), Wilms' tumour (kidney cancer), childhood rhabdomyosarcoma (RMS), Skin cancer and testicular and uterus cancers in both adult and pediatric patients. Actinocin 0.5 mg Injection can be used alone or in combination with other chemotherapy drugs as determined by the doctor. Actinocin 0.5 mg Injection works by inhibiting the reproduction cells (especially abnormal cells).

Actinocin 0.5 mg Injection may cause some common side effects including nausea, vomiting, mouth ulcers and loss of appetite. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine and some people may develop serious side effects while taking it. Actinocin 0.5 mg may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before using Actinocin 0.5 mg, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Actinocin 0.5 mg Injection is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may conduct several tests such as blood tests, and physical examinations both before and during treatment with this Actinocin 0.5 mg Injection.

Actinocin 0.5 mg Injection is given by injection into a vein under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

Uses of Actinocin 0.5 mg Injection

• Ewing’ sarcoma (bone cancer)
• Rhabdomyosarcoma (muscle cancer)
• Melanoma (skin cancer)
• Wilms’ tumour (kidney cancer usually appears in children)
• Testicular and uterus cancer
  

Benefits of Actinocin 0.5 mg Injection

Ewing’s sarcoma (bone cancer): Ewing's sarcoma is a rare type of cancer that primarily affects the bones or soft tissues. The most common symptom of Ewing's sarcoma is pain and swelling around the affected bone or soft tissue. Other symptoms may include a noticeable lump or mass, fever, fatigue, weight loss, and bone fractures. It usually affects children and young adults. Actinocin 0.5 mg Injection helps to treat Ewing’s sarcoma. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine, and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Rhabdomyosarcoma (muscle cancer): Rhabdomyosarcoma is a type of cancer that arises from the soft tissues, specifically the skeletal muscle cells. It is the most common soft tissue sarcoma in children and adolescents, although it can also occur in adults. The symptoms of rhabdomyosarcoma vary depending on the location of the tumour. Common signs and symptoms may include a visible or palpable mass or swelling, pain or tenderness at the tumour site, and limited range of motion. It may be given alone or in combination with other medicines to remove the tumour, prevent its spread, and minimize the risk of recurrence.

Melanoma (skin cancer): Melanoma is a type of skin cancer that develops from melanocytes, the cells that produce the pigment melanin. Melanoma can occur anywhere on the body, including areas not exposed to the sun. It is considered the most aggressive form of skin cancer because it has the potential to spread to other parts of the body if not detected and treated early. The most common sign of melanoma is a new or existing mole that undergoes changes in size, shape, colour, or texture. Actinocin 0.5 mg Injection is given only under medical guidance. Consult your doctor if you have any doubts.

Wilms’ tumour (kidney cancer usually appears in children): Wilms' tumour, also known as nephroblastoma, is a type of kidney cancer that primarily affects children. It is the most common type of kidney cancer in children, typically occurring between the ages of 2 and 5 years old. The most common symptoms of Wilms' tumour may include a painless, palpable mass or swelling in the abdomen, usually on one side. Other possible signs and symptoms include abdominal pain, blood in the urine, high blood pressure, fever, and weight loss. Actinocin 0.5 mg Injection is used along with other medicines or treatment modalities such as surgery, radiation or chemotherapy depending on the stage or severity of the cancer and the condition of the patient. Follow the doctor’s instructions carefully to get the most benefit.

Testicular cancer: Testicular cancer is a type of cancer that develops in the testicles, which are the male reproductive organs that produce sperm and testosterone. The most common symptom of testicular cancer is a painless lump or swelling in the testicles. Actinocin 0.5 mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.

Uterine (Endometrial) Cancer: Uterine cancer, also known as endometrial cancer, affects the lining of the uterus (endometrium). It is the most common cancer of the female reproductive system and typically affects women after menopause. The most common symptom of uterine cancer is abnormal vaginal bleeding, particularly postmenopausal bleeding. Actinocin 0.5 mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in women. It is given as an injection by a doctor or nurse and should not be self-administered.

Side Effects of Actinocin 0.5 mg Injection

Actinocin 0.5 mg Injection adverse effects are based on different factors and some of them are your medical history, immunity system, etc. Symptoms between two people will never be the same.

Most Common Side Effects of Actinocin 0.5 mg Injection

• Diarrhea
• Hair Loss
• Constipation
• Chest Pain
• Tingling in Feet and Feet
• Skin Rashes
• Damage of Soft Tissue

Common Side Effects of Actinocin 0.5 mg Injection

• Liver problems Severe Bleeding
• Tumor Lysis Syndrome

How to Use Actinocin 0.5 mg Injection?

Actinocin 0.5 mg Injection is given intravenously under the supervision of your doctor or a nurse in a hospital. Self-administration is not recommended to the patient.

How Actinocin 0.5 mg Injection Works?

Actinocin 0.5 mg Injection mainly acts as a nucleic Acid Synthesis Inhibitor, and a protein Synthesis Inhibitor, that drug bind to DNA and inhibits the RNA synthesis (prevent an elongation of RNA polymerase) and, in a consequence, with a protein synthesis.

Safety Advices Actinocin 0.5 mg Injection

Alcohol

Unsafe

Pregnancy

Unsafe

Kidney

Safe

Breastfeeding

Unsafe

Driving

Use with Caution

Liver

Use with Caution

References

1. Dactinomycin Injection Prescribing Information, Drugs.com, Available Form

2. Dactinomycin, Drug Bank Online, Available Form

3. Cosmegen For Injection, (dactinomycin For Injection), Merck & Co. Inc, Product Leaflet