Denu 60 mg PFS

Introduction of Denu PFS

Denu 60 mg PFS is used to treat osteoporosis (a condition in which bone density decreases and bones become weak and brittle) in men and postmenopausal women who are at high risk for bone fractures and have not responded to other drug treatments for osteoporosis. Denu PFS Injection is also used to treat bone loss in men with prostate cancer and women with breast cancer who are being treated with drugs that cause bone loss. Denu 60 mg also reduces the risk of bone fractures in patients with bone cancer and multiple myeloma (a type of blood cancer). 

Denu 60 mg Injection can be used under the guidance of a doctor or any other medical staff. For better results, you must take this medicine at the same time regularly. You have to consume Vitamin D and calcium tablets during this treatment. 

Denu 60 mg PFS has many adverse effects such as constipation, leg or joint pain, nerve pain, urinary tract infection, musculoskeletal, rash, hair loss, etc. 

Denu 60 mg is not recommended for any pregnant woman. But consult your doctor before using this medicine while breastfeeding. Do not use this medicine if your blood calcium is too low. If you are planning to have any thyroid or dental surgery then, ask your doctor before starting the medicine.

Denu 60 mg PFS is not recommended for use in children and adolescents below 18 years of age.

Uses of Denu PFS

Osteoporosis: Denu 60 mg PFS is used to treat osteoporosis (a condition in which bone density decreases and bones become weak and brittle) in men and postmenopausal women who are at high risk for bone fractures and have not responded to other drug treatments for osteoporosis.

Osteolytic bone metastases of solid tumours: Denu PFS Injection is used to treat bone loss in men with prostate cancer and women with breast cancer who are being treated with drugs that cause bone loss.

Benefits of Denu PFS

Denu 60 mg Injection has been shown to be effective in reducing the risk of fractures in patients with osteoporosis and increasing bone density and strength, resulting in a lower risk of fractures in the spine, hip, and other bones.

Denu PFS Injection effective in reducing the risk of fractures in patients with bone metastases (spread of cancer to the bones).

Side Effects of Denu PFS

​​​​Denu 60 mg PFS may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​

Most Common Side Effects of Denu PFS

• Arm or leg pain
• Joint pain
• Muscle or bone pain
• Constipation,
• Abdominal discomfort
• Hair loss
• Skin rash
• Tingling, pain, or numbness that moves down your leg

Common Side Effects of Denu PFS

• Upper respiratory tract infection
• Frequent or painful urination, blood in urine, inability to hold urine
• Musculoskeletal
• Severe leg or joint pain

How to Use Denu PFS?

​​Denu 60 mg is given subcutaneously and administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of Denu will depend on the clinical condition of the patient's age and medical history, and other factors. It is important to follow your doctor's instructions carefully when using this medication.​

How Denu PFS Works?

Denu PFS Injection is a monoclonal antibody that works by inhibiting the activity of a protein called RANKL (receptor activator of nuclear factor kappa-B ligand), which is involved in bone resorption (the process by which bone is broken down and minerals are released into the bloodstream).

Safety Advices Denu PFS

Breastfeeding

Unsafe

Driving

Safe

Liver

Safe

Alcohol

Unsafe

Pregnancy

Unsafe

Kidney

Safe

References

1. Prolia, (denosumab) Injection, For Subcutaneous Use, Amgen Inc. Usa, [revised: 05/2022], Product Leaflet 

2. Prolia 60 Mg, Amgen Europe B.v. [revised In April 2022 According To Mohs Guidelines ], Available Form 

3. Prolia 60 Mg Solution For Injection In Pre-filled Syringe, Amgen Technology (Ireland) Unlimited Company, Product Leaflet 

4. Prolia, (denosumab) Injection, For Subcutaneous Use, Amgen Manufacturing Limited, A Subsidiary Of Amgen Inc. Product Monograph 

5. Denosumab (prolia) 60mg Sc Twice Yearly For Osteoporosis Information For Treatment Of Adults In Primary Care, North Of Tyne And Gateshead Area Prescribing Committee Page 4 Of 4, Available Form