Denu 60 mg PFS | 60 mg in 1 ml PFS

Introduction of Denu 60 mg PFS

Denu 60 mg PFS is used to treat osteoporosis (a condition in which bone density decreases and bones become weak and brittle) in men and postmenopausal women who are at high risk for bone fractures and have not responded to other drug treatments for osteoporosis. Denu 60 mg is also used to treat bone loss in men with prostate cancer and women with breast cancer who are being treated with drugs that cause bone loss. Denu 60 mg PFS also reduces the risk of bone fractures in patients with bone cancer and multiple myeloma (a type of blood cancer).

Denu 60 mg PFS can be used under the guidance of a doctor or any other medical staff. For better results, you must take this medicine at the same time regularly. You have to consume Vitamin D and calcium tablets during this treatment.

Denu 60 mg PFS has many adverse effects such as constipation, leg or joint pain, nerve pain, urinary tract infection, musculoskeletal, rash, hair loss, etc.

Denu 60 mg PFS is not recommended for any pregnant woman. But consult your doctor before using this medicine while breastfeeding. Do not use this medicine if your blood calcium is too low. If you are planning to have any thyroid or dental surgery then, ask your doctor before starting the medicine.

Denu 60 mg PFS is not recommended for use in children and adolescents below 18 years of age.

Uses of Denu 60 mg PFS

Osteoporosis: Denu 60 mg PFS are used to treat osteoporosis (a condition in which bone density decreases and bones become weak and brittle) in men and postmenopausal women who are at high risk for bone fractures and have not responded to other drug treatments for osteoporosis.

Osteolytic bone metastases of solid tumors: Denu 60 mg PFS are used to treat bone loss in men with prostate cancer and women with breast cancer who are being treated with drugs that cause bone loss.

Benefits of Denu 60 mg PFS

Denu 60 mg PFS has been shown to be effective in reducing the risk of fractures in patients with osteoporosis and increasing bone density and strength, resulting in a lower risk of fractures in the spine, hip, and other bones.

Denu 60 mg effective in reducing the risk of fractures in patients with bone metastases (spread of cancer to the bones).

Side Effects of Denu 60 mg PFS

​​​​Denu 60 mg PFS may cause some side effects. If you experience any of these side effects, contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.

Most Common Side Effects of Denu 60 mg PFS

• Arm or leg pain
  
• Joint pain
• Muscle or bone pain
• Constipation,
• Abdominal discomfort
• Hair loss
• Skin rash
• Tingling, pain, or numbness that moves down your leg

Common Side Effects of Denu 60 mg PFS

• Upper respiratory tract infection
  
• Frequent or painful urination, blood in urine, inability to hold urine
• Musculoskeletal
• Severe leg or joint pain

How to Use Denu 60 mg PFS?

​Denu 60 mg PFS can be administered to you subcutaneously (under the skin) by a doctor or nurse. You should also take calcium and vitamin D supplements while being on treatment with Denu 60 mg. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.

How Denu 60 mg PFS Works?

Denu 60 mg PFS is a monoclonal antibody that works by inhibiting the activity of a protein called RANKL (receptor activator of nuclear factor kappa-B ligand), which is involved in bone resorption (the process by which bone is broken down and minerals are released into the bloodstream).

Safety Advices Denu 60 mg PFS

Breastfeeding

Unsafe

Driving

Safe

Kidney

Use with Caution

Liver

Use with Caution

Alcohol

Unsafe

Pregnancy

Unsafe

References

1. Parole, (denosumab) Injection, For Subcutaneous Use, Amgen Inc. USA, [revised: 05/2022], Product Leaflet 

2. Prolia 60 Mg, Amgen Europe B.v.  [revised In April 2022 According To Mohs Guidelines], Available From 

3. Prolly 60 Mg Solution For Injection In Pre-filled Syringe, Amgen Technology (Ireland) Unlimited Company, Product Leaflet 

4. Parole, (denosumab) Injection, For Subcutaneous Use, Amgen Manufacturing Limited, A Subsidiary Of Amgen Inc. Product Monograph 

5. Denosumab (prolia) 60mg Sc Twice Yearly For Osteoporosis Information For Treatment Of Adults In Primary Care, North Of Tyne And Gateshead Area Prescribing Committee Page 4 Of 4, Available Form