Introduction of Eligard Depot 45 mg Injection
Eligard Depot 45 mg Injection is a gonadotropin-releasing hormone (GnRH) agonist. It is used in the treatment of conditions related to hormone regulation, particularly those associated with the reproductive system. It is also used to treat prostate cancer in men, breast cancer and endometriosis in women and precocious puberty (early puberty) in children. The safety and effectiveness of Eligard Depot 45 mg Injection have not been established in pediatric patients less than 1 year old.
Eligard Depot 45 mg Injection may cause some common adverse effects including acne/seborrhea, vaginitis/vaginal bleeding/vaginal discharge, pain, rash including erythema multiforme, headache, and vasodilation, injection site pain, increased weight, headache, altered mood, and injection site swelling. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7–12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
People who have experienced any type of allergic reaction to Eligard Depot 45 mg Injection or similar drugs should not take Eligard Depot 45 mg. Females who are or may be pregnant or have undiagnosed uterine bleeding should not receive Eligard Depot 45 mg Injection. Seizures have been observed in patients taking Eligard Depot 45 mg Injection patients who have a history of seizures or conditions related to seizures or in patients who are taking medications that are connected to seizures. Seizures have also been reported in patients without any of these conditions.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
Eligard Depot 45 mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Uses of Eligard Depot 45 mg Injection
Endometriosis: Eligard Depot 45 mg Injection is used for the management of endometriosis, including pain relief and reduction of endometriotic lesions.
Uterine Fibroids: Eligard Depot 45 mg Injection is used before fibroid surgery to improve anaemia due to vaginal bleeding from fibroids for patients in whom 3 months of hormonal suppression is deemed necessary. The duration of therapy with Eligard Depot 45 mg Injection is limited to 3 months. The symptoms associated with fibroids will return after stopping therapy.
Advanced Prostate Cancer: Eligard Depot 45 mg Injection is used for the treatment of advanced prostate cancer.
Central Precocious Puberty (CPP): Eligard Depot 45 mg Injection is used for the treatment of children with central precocious puberty (CPP). It is not known if Eligard Depot 45 mg is safe and effective in children less than 1-year-old.
Benefits of Eligard Depot 45 mg Injection
In Treatment of Endometriosis
Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhoea and feeling sick. It can also make it difficult to get pregnant. Eligard Depot 45 mg Injection acts by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.
In Treatment of Uterine fibroids
Uterine fibroids are non-cancerous growths of the uterus that often appear during the childbearing years. Eligard Depot 45 mg can help control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, and lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further.
In Treatment of Advanced prostate cancer
The prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperm in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Eligard Depot 45 mg Injection may decrease or stops the growth of cancer cells by decreasing the amount of testosterone (a natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
In Treatment of Precocious puberty (premature puberty)
When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Eligard Depot 45 mg Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is given by a doctor and should not be self-administered. Follow your doctor’s instructions carefully for the most benefit.
Side Effects of Eligard Depot 45 mg Injection
Like all medication, Eligard Depot 45 mg Injection may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.
Most Common Side Effects of Eligard Depot 45 mg Injection
- Dry mouth
- Bone pain
- Slow Speech
- Feeling thirsty
- Weight Fluctuation
- Muscle pain
- Runny nose
- Abdominal Pain
- Difficulty in remembering things
- Irregular menstruation
- Vaginal discharge
Common Side Effects of Eligard Depot 45 mg Injection
- Blurred Vision
- Difficult Breathing
- Severe Headache
- Decreased Sexual Desire
- Change in Breast Size
- Hot flashes
- Intense sweating
- Tingling sensation on feet and palms
- Feeling Uneasiness
- Decreased Testicles size
How to Use Eligard Depot 45 mg Injection?
Your healthcare professional or nurse will give you this medicine. Kindly do not self-administer.
How Eligard Depot 45 mg Injection Works?
Eligard Depot 45 mg Injection is an agonist of Gonadotropin-releasing hormone receptor, which leads to suppression of Gonadotrope secretion of Luteinizing Hormone and Follicle stimulating hormone. Initially, it increases the level of Estrogen and Testosterone irrespective of sex. But a continuation of this therapy decreases the level of Testosterone in males and estrogen in females.
Safety Advices Eligard Depot 45 mg Injection
It is not recommended to consume alcohol while taking Eligard Depot 45 mg Injection. Alcohol may increase the risk of side effects or interfere with the effectiveness of the Eligard Depot 45 mg. It is best to talk to your doctor or pharmacist before consuming alcohol while taking any medicine.
It is not recommended to breastfeed while taking Eligard Depot 45 mg. Eligard Depot 45 mg Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Eligard Depot 45 mg, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.
Use of Eligard Depot 45 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Eligard Depot 45 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.
Eligard Depot 45 mg Injection may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Eligard Depot 45 mg.
If you suffering from liver disease, please consult the doctor before taking Eligard Depot 45 mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.
If you suffering from kidney disease, please consult the doctor before taking Eligard Depot 45 mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.
1. Leuprolide Acetate for Depot Suspension, 3-month Formulation, Abbott Laboratories, Product Leaflet
2. Lupron Depot-ped (Leuprolide Acetate for Depot Suspension), for Intramuscular Use, Abbvie Inc. Product Leaflet