Evelimus 10 mg Tablet | 10 Tablets in 1 Strip

Introduction of Evelimus 10 mg Tablet

Evelimus 10 mg Tablet is an anticancer medicine used for the treatment of various cancers such as the pancreas, stomach, intestines, or lungs that have spread or progressed and that cannot be treated with surgery. Evelimus 10 mg Tablet is used for the treatment of breast cancer in postmenopausal women with advanced hormone receptor-positive, and HER2-negative. It is also used for the treatment of adult patients with advanced kidney cancer after failure of treatment with sunitinib or sorafenib. Evelimus 10 mg Tablet is also used to treat kidney tumours in people with tuberous sclerosis complex (a genetic condition that causes tumours to grow in many organs including the brain spinal cord, nerves, eyes, lungs, heart, kidneys, and skin). Evelimus 10 mg is used to treat subependymal giant cell astrocytoma (a type of brain tumour) in adults and children 1 year of age and older who have tuberous sclerosis complex. It may be used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in certain adults who have received kidney transplants.

Evelimus 10 mg Tablet may cause some common adverse effects including mouth ulcers, low white blood cell count, infections, low platelet count, nail and skin colour change, fatigue, nausea and vomiting, diarrhoea, decreased appetite, taste change, elevated blood sugar levels and cholesterol. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc). Always seek medical advice if you have increased thirst or increased frequency of urination, or suffer from shortness of breath, cough or fever.

Before taking Evelimus 10 mg, inform the doctor about your past and present medical complications such as if you have any kidney or liver disease, diabetes, high cholesterol levels in the blood, any infections, hepatitis-B infection or any other medical conditions and if you are using any prescription medicines and non-prescription medicines, herbal, vitamins, etc. Many other medicines will interact with this medicine, so please make sure inform to the doctor. This medicine is not recommended for use in pregnant women and breastfeeding women, it may cause birth defects. Evelimus 10 mg may affect fertility. However, it is important to use birth control to prevent pregnancy because Evelimus 10 mg can harm an unborn baby. You should also avoid having live or live-attenuated vaccines while receiving this Evelimus 10 mg. These include herpes zoster (Zostavax) for shingles prevention, oral polio, measles, nasal flu vaccine, rotavirus and yellow fever vaccines.

​Evelimus 10 mg Tablet can be taken by mouth with or without food. Swallow the whole tablet with a glass of water. Do not crush, break, or chew the tablets. Take your dose around the same time every day. It is important to make sure you are taking the correct amount of medication every time. Before every dose, check that what you are taking matches what you have been prescribed. If you miss a dose and it has been less than 6 hours since your regular dose time, take it as soon as you remember. If it has been more than 6 hours, skip the dose. Do not take 2 doses at once to make up for a missed dose.

Uses of Evelimus 10 mg Tablet

Breast cancer: Evelimus 10 mg Tablet is used for the treatment of postmenopausal women with advanced hormone receptor-positive, HER2-negative breast cancer in combination with exemestane, after the failure of treatment with letrozole or anastrozole. The symptoms include nipple changes, such as inversion, discharge, or a scaly or itchy rash, pain or tenderness in the breast, changes in breast size or shape, unexplained weight loss or loss of appetite, Fatigue or weakness, etc.

Neuroendocrine Tumors (NET): Evelimus 10 mg Tablet may also use to prevent neuroendocrine tumours (Neuroendocrine tumours are rare and can occur anywhere in the body. Most neuroendocrine tumours occur in the lungs, appendix, small intestine, rectum and pancreas.

Kidney cancer: Evelimus 10 mg Tablet is used for the treatment of adult patients with kidney cancer after the failure of treatment with sunitinib or sorafenib. The symptoms include high blood pressure, swelling in the ankles or legs, fatigue, weight loss and loss of appetite low red blood cell count, etc.

Tuberous Sclerosis Complex (Genetic Disease)(TSC)-Associated Renal Angiomyolipoma: Evelimus 10 mg Tablet is used for the treatment of adult patients with renal angiomyolipoma and TSC, not requiring immediate surgery.

Tuberous Sclerosis Complex (TSC)-Associated Subependymal Giant Cell Astrocytoma (SEGA) (Brain Tumour): Evelimus 10 mg Tablet is used in adult and pediatric patients aged 1 year and older with TSC for the treatment of SEGA that requires therapeutic intervention but cannot be curatively resected.

Benefits of Evelimus 10 mg Tablet

Evelimus 10 mg Tablet is indicated to patients dealing with various cancers such as breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. Evelimus 10 mg Tablet travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreasing the activity of the immune system of the body and prevents the rejection of the transplanted organ. Evelimus 10 mg works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumours in the brain or kidneys.

Side Effects of Evelimus 10 mg Tablet

​​​Evelimus 10 mg Tablet may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​​​

Most Common Side Effects of Evelimus 10 mg Tablet

• Infection
• Urinary issues
• Hypertension, rise in cholesterol or triglycerides
• Stomach pain, nausea, diarrhoea and/or constipation
• Headache
• Swelling in your legs or feet

Common Side Effects of Evelimus 10 mg Tablet

• Swelling in legs and feet
• Blood in stools and urine
• Burning sensation during urination
• Mouth sores
• Headache
• Tiredness
• Nausea

How to Use Evelimus 10 mg Tablet?

​​Evelimus 10 mg Tablet can be taken by mouth with or without food. Swallow the whole tablet with a glass of water. Do not crush, break, or chew the tablets. Take your dose around the same time every day. It is important to make sure you are taking the correct amount of medication every time. Before every dose, check that what you are taking matches what you have been prescribed. If you miss a dose and it has been less than 6 hours since your regular dose time, take it as soon as you remember. If it has been more than 6 hours, skip the dose. Do not take 2 doses at once to make up for a missed dose.​

How Evelimus 10 mg Tablet Works?

Evelimus 10 mg Tablet contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors. It works by decreasing the activity of the immune system of the body and preventing the rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Safety Advices Evelimus 10 mg Tablet

Breastfeeding

Unsafe

Alcohol

Unsafe

Pregnancy

Unsafe

Liver

Use with Caution

Driving

Unsafe

Kidney

Safe

References

1. Everolimus, Bc Cancer Drug Manual, Product Leaflet

2. Afinitor (everolimus) Tablets For Oral Administration, Novartis Pharma Stein Ag, Product Leaflet

3. Afinitor, (everolimus) Tablets, For Oral Use, Novartis Pharmaceuticals Corporation, Product Monograph

4. Afinitor 2.5 Mg, 5 Mg, 10 Mg Tablets, Novartis Farmacéutica Sa, Product Leaflet

5. Everolimus (afinitor), Avaliable Form

6. Everolimus, MedlinePlus, Avaliable Form

7. Everolimus, Drugs.com, Avaliable Form