Factocel VIII 250 IU Injection | 250 IU in 1 Vial

Introduction of Factocel VIII 250 IU Injection

Factocel VIII 250 IU Injection is an antihemophilic factor derived from human plasma and is used to control and prevent bleeding episodes or to aid in emergency and elective surgery in adult and pediatric patients with haemophilia A (inherited Factor VIII deficiency). This medicine is not indicated for the treatment of von Willebrand disease (a bleeding disorder caused by low levels of a clotting protein in the blood.

Factocel VIII 250 IU Injection may cause some common side effects including nervousness, headache, abdominal pain, nausea, numbness and blurred vision, angioedema, burning and stinging at the infusion site, chills, flushing, generalised urticaria, hives, hypotension, lethargy, restlessness, tachycardia, tightness in the chest, tingling, vomiting, wheezing. These side results may be temporary and commonly leave on their own. However, if they persist or get worse, tell your doctor.

Factocel VIII 250 IU is not recommended if you are allergic to any of the ingredients or to mouse or hamster proteins. Tell your doctor about all your medical conditions and if you are pregnant or planning to become pregnant, or are breast-feeding or planning to breast-feed. Also tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, vitamins, or herbal supplements

Factocel VIII 250 IU Injection is given in a hospital or clinic by a doctor or nurse. Your doctor will decide when to give the injection, so always follow your doctor's advice.The dose and the way regularly you're taking it's going to rely on what you're taking it for. You may also be given other medicines as part of your treatment.You need to take this medicinal drug for so long as it's far prescribed.

Uses of Factocel VIII 250 IU Injection

Prevents or Controls Bleeding In Patients With Hemophilia A: Factocel VIII 250 IU Injection contains human coagulation factor VIII. It is used to treat haemophilia (haemophilia A). Hemophilia A is an inherited bleeding disorder that prevents blood from clotting normally due to a lack of clotting factor, Factor VIII. This Injection is used to control or prevent bleeding episodes in individuals with haemophilia. Factocel VIII 250 IU also helps to perform surgery on hemophilic individuals.

Benefits of Factocel VIII 250 IU Injection

Prevents or Controls Bleeding In Patients With Hemophilia A: The use of Factocel VIII 250 IU Injection has proven to be effective in addressing the deficiency of circulating factor VIII in patients with haemophilia A, a sex-linked hereditary disorder of blood coagulation. This disorder causes a decrease in the level of factor VIII, resulting in excessive bleeding into joints, muscles, or internal organs. Whether it occurs spontaneously or due to accidental or surgical trauma, Factocel VIII 250 IU Injection has demonstrated its ability to prevent or control such bleeding.

Side Effects of Factocel VIII 250 IU Injection

​As with all medicines, Factocel VIII 250 IU may have side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. Tell your doctor if they persist or if you're worried about them.​​

Most Common Side Effects of Factocel VIII 250 IU Injection

• ​chills 
• Flushing
• Generalised urticaria
• Hives
• Hypotension 
• Lethargy 
• Restlessness
• Tachycardia
• Tightness of the chest
• Tingling
• Vomiting
• Wheezing​
  

Common Side Effects of Factocel VIII 250 IU Injection

• Nervousness 
• Headache 
• Abdominal pain 
• Nausea
• Paresthesia
• Blurred vision
• Angioedema 
• Burning and stinging at the infusion site
  

How to Use Factocel VIII 250 IU Injection?

A doctor or nurse will give you Factocel VIII 250 IU Injection in a hospital or clinic. It is important that you always follow your doctor's advice about the timing of your injection. The dose and frequency of administration will depend on the purpose of your treatment. You may also be given other medicines as part of your treatment. It is important that you take all of your medicine for the full prescribed time.

How Factocel VIII 250 IU Injection Works?

Factocel VIII 250 IU Injection contains human coagulation factor VIII. It is essential for blood clotting and haemostasis. Activated Factor VIII (Factor VIIIa) acts as a cofactor for the activation of Factor IX to IXa, which cascades to activate Factor X to Xa. The action of activated Factors Va and Xa converts circulating pro-thrombin to thrombin. Subsequently, thrombin converts fibrinogen to fibrin monomer, cascading to form linear fibrin polymer. Through the action of Factor XIII, the fibrin monomer is cross-linked to form fibrin clots, resulting in the arrest of bleeding episodes.

Safety Advices Factocel VIII 250 IU Injection

Kidney

Not known

Liver

Not known

Alcohol

Unsafe

Driving

Safe

Pregnancy

Safe

Breastfeeding

Safe

References

1. Immunate 250 Iu Fviii/190 Iu Vwf Powder And Solvent For Solution For Injection, Avaliable Form

2. Advate 250 Iu Powder And Solvent For Solution For Injection, Baxalta Belgium Manufacturing Sa, Product Leaflet

3. Advate 250 Iu Powder For Injection With Diluent, Takeda New Zealand Limited, Product Leaflet

4. Koate Prescribing Information, Drugs.com, Avaliable Form

5. Dried Human Antihaemophilic Factor Viii Fraction I.p. 250 Iu, Intas Pharmaceuticals Ltd, Product Leaflet

6. Advate [antihemophilic Factor (recombinant), Plasma/albumin-free Method] For Intravenous Use, Lyophilized Powder For Reconstitution, Baxter Healthcare Corporation, Product Leaflet