Fibrogen I Injection | 1 gm in 1 Injection

Introduction of Fibrogen I Injection

Fibrogen I Injection is a medication specifically designed to address acute bleeding episodes in both pediatric and adult patients who suffer from congenital fibrinogen deficiency. This condition encompasses afibrinogenemia and hypofibrinogenemia, which are rare genetic bleeding disorders. Afibrinogenemia is characterized by the absence or extremely low levels of fibrinogen, a crucial protein involved in blood clot formation. Consequently, individuals with this disorder may encounter spontaneous bleeding episodes, particularly in the joints, muscles, and soft tissues. Moreover, they may also experience prolonged bleeding following injuries, surgeries, or dental procedures. On the other hand, hypofibrinogenemia is marked by insufficient levels of fibrinogen, leading to excessive bleeding and an extended bleeding time. It is important to note that this medication is not suitable for the treatment of dysfibrinogenemia, a clotting disorder

Fibrogen I Injection may cause certain typical side effects such as fever and headache. It may also cause less common but more serious side effects such as chest pain, sudden coughing, wheezing, rapid breathing, coughing up blood, numbness or weakness, slurred speech, and problems with vision or balance. If you experience any of these symptoms while taking Fibrogen I Injection, you should stop taking the medicine and seek immediate medical advice from your doctor.

Before using this Fibrogen I Injection, tell your doctor about your past and present medical history. if you have had any stroke or blood clot problems and severe allergic reactions or any other medical conditions. You should also inform your doctor if you are currently using any prescription or non-prescription medicines, vitamins, dietary supplements, or herbal products. If you are pregnant or becoming pregnant and breast-feeding. Before using this medicine you should consult your doctor.

Fibrogen I Injection is given in a hospital or clinic by a doctor or nurse. Your doctor will decide when to give you your injection, so always follow your doctor's advice. The dose and how often you take it will depend on what you are taking it for. You may also be given other medicines as part of your treatment. You should take this medicine for as long as it is prescribed.

Uses of Fibrogen I Injection

Treatment of Congenital Fibrinogen Deficiency: Fibrogen I Injection is used for the treatment of acute bleeding episodes in pediatric and adult patients with congenital fibrinogen deficiency. The symptoms of congenital fibrinogen deficiency can include spontaneous bleeding, such as nosebleeds, bruising, and prolonged bleeding after injury or surgery. In some cases, the disorder can also cause internal bleeding, which can be life-threatening.

Benefits of Fibrogen I Injection

Congenital fibrinogen deficiency is a rare genetic disorder characterized by the absence or inadequate levels of fibrinogen in the blood. Fibrinogen is a protein that plays a crucial role in blood clotting. Without enough fibrinogen, the blood cannot form clots properly, leading to bleeding episodes that can range from mild to severe. Fibrogen I Injection is administered intravenously to increase the production of erythropoietin (EPO), a hormone that stimulates the production of red blood cells in the bone marrow.

Side Effects of Fibrogen I Injection

As with all medicines, Fibrogen I Injection may cause side effects that do not require medical attention and will disappear as your body adjusts to the medicine. Tell your doctor if they persist or if you're worried about them.

Most Common Side Effects of Fibrogen I Injection

• Thromboembolic events
  
• Injection site reactions

Common Side Effects of Fibrogen I Injection

• Fever
• Headache

How to Use Fibrogen I Injection?

The administration of Fibrogen I Injection is done intravenously in a hospital or clinic under the supervision of a doctor or nurse. It is important to follow your doctor's instructions regarding the timing of the injection. The dose and frequency of administration will vary depending on the purpose of the treatment. Your doctor may also prescribe other medicines as part of your overall treatment plan. It is important that you take this medicine for the full course of treatment prescribed by your doctor.

How Fibrogen I Injection Works?

Fibrogen I Injection works by inhibiting the activity of an enzyme called prolyl hydroxylase, which normally breaks down HIF. By inhibiting this enzyme, Fibrogen I Injection increases the levels of HIF in the body, which in turn stimulates the production of EPO and the creation of new red blood cells.

Safety Advices Fibrogen I Injection

Kidney

Use with Caution

Driving

Safe

Breastfeeding

Unsafe

Kidney

Use with Caution

Alcohol

Unsafe

Pregnancy

Unsafe

References

1. Fibrinogen Concentrate (human) Powder And Solvent For Solution For Injection / Infusion 1 G/vial Reconstituted With 50 Ml Of Diluent, Octapharma Pharmazeutika Produktionsges. M.b.h, Product Monograph

2. Riastap, Fibrinogen Concentrate (Human) Lyophilized Powder For Solution For Intravenous Injection, Csl Behring Gmbh, Product Leaflet

3. Riastap, (human Fibrinogen), Csl Behring (australia) Pty Ltd, Product Leaflet

4.Fibryga, [fibrinogen (human) Lyophilized Powder For Reconstitution, For Intravenous Use,octapharma Pharmazeutika Produktionsges.m.b.h. Product Leaflet

5. RiaSTAP 1 g, powder and diluent for solution for injection, CSL Behring GmbH, Product Leaflet