Introduction of Hamsyl 3750 IU Injection

• Hamsyl 3750 IU Injection is an anti-cancer medicine that is used in the treatment of various types of cancer of the blood. It can also be used to treat Hodgkin's disease. Sometimes it is used with other medicines in combination chemotherapy.
  
  Hamsyl 3750 IU may cause some common adverse effects including allergic response, rash, increased blood glucose level, diarrhea, and abdominal pain. If they bother you or seem severe, tell your prescriber or health care professional. There may be ways that you can reduce or avoid these effects. You will need regular blood tests to check your blood cells as well as your heart, liver and blood sugar levels.
  
  If you have heart disease, liver or kidney problems, or are taking medicines to treat infections, you should tell your doctor before taking Hamsyl 3750 IU Injection. Many other medicines may have an effect on, or be affected by, this medicine, so tell your doctor about all the medicines you are taking. Hamsyl Injection is not recommended during pregnancy or lactation. Both men and women should use effective contraception while taking this medicine to avoid becoming pregnant.
  
  Hamsyl Injection is administered by injection under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you should have your injection. This may change from time to time depending on what you are being treated for. You should take this medicine exactly as your doctor or health care professional advises. You can get very serious side effects if you do not take it properly or if you take too much. You should not stop taking this medicine unless your doctor tells you to. It may take several weeks or months before you see or feel the benefits of this medicine.
  

Uses of Hamsyl 3750 IU Injection

• • ALL (Acute lymphoblastic leukaemia)
  • NHL (Non Hodgkin's lymphoma)
    

Benefits of Hamsyl 3750 IU Injection

• In blood cancer (acute lymphoblastic leukaemia): Blood cancer, also known as leukaemia, is a cancer of the tissues that make up blood, which reduces the body's ability to fight infection. Hamsyl 3750 IU Injection works by killing or stopping the growth of cancer cells and also by preventing the cancer cells from multiplying. It is an effective but very toxic medicine and you should discuss with your doctor about the risks and benefits of this medicine. It would help if you drank plenty of water to stay hydrated and avoid alcohol while receiving this treatment.

   Hodgkin's disease: Hodgkin's disease is a form of lymphoma, a blood cancer that starts in the lymph system. The lymph system helps the immune system remove waste and fight infection. Hamsyl 3750 IU works by killing or stopping the growth of cancer cells and preventing cancer cells from multiplying. Follow your doctor's instructions carefully and tell your doctor or health care professional if any of the side effects bother you.

Side Effects of Hamsyl 3750 IU Injection

• ​​​​Like all medicines, Hamsyl 3750 IU Injection may cause side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. Tell your doctor if they persist or if you're worried about them.​
  

Most Common Side Effects of Hamsyl 3750 IU Injection

• • Nausea
  • Vomiting
  • Weakness
  • Loss of appetite
  • Diarrhoea
  • Epigastric pain
  • Swelling over hands/ feet and ankles
  • Injection site reaction ( like pain, redness, swelling)
  • Irritability

Common Side Effects of Hamsyl 3750 IU Injection

• • Drowsiness
  • Acute Pancreatitis ( Pain in abdomen, unable to eat, swollen and tender abdomen, Rapid pulse)
  • ​Headache
  • Tiredness
  • Irritability
  • Stomach cramps
  • Weight loss
    

How to Use Hamsyl 3750 IU Injection?

• Hamsyl 3750 IU Injection is available in liquid (injectable) IM and IV forms, which should be administered by a healthcare professional under medical supervision. The dosage and frequency of administration will be determined by your physician based on your medical condition and a number of other factors.
  

How Hamsyl 3750 IU Injection Works?

• Hamsyl 3750 IU Injection is more effective than native asparaginase in converting aspargine to aspartic acid and ammonia. It helps produce oxaloacetate which is needed for general cellular metabolism. Some malignant cells lose the ability to produce asparagine and so losing exogenous sources of asparagine leads to cell death.
  

Safety Advices Hamsyl 3750 IU Injection

Pregnancy

Unsafe

The use of Hamsyl 3750 IU Injection is not recommended in pregnant women as it may cause harm to the foetus if administered to a pregnant woman.

Alcohol

Unsafe

Drinking alcohol while taking Hamsyl 3750 IU is generally not recommended. It may increase the risk of liver damage and it is best to avoid alcohol or to limit the amount of alcohol you drink while you are taking this medicine.

Driving

Safe

Hamsyl 3750 IU Injection does not alter or impair the ability to drive or use machines.

Breastfeeding

Unsafe

There are no data on the presence of Hamsyl 3750 IU or its metabolites in human milk or effects on nursing infants or lactation. Because of the potential for serious adverse reactions in nursing infants, women should be advised not to breastfeed during treatment with Hamsyl 3750 IU and for 2 weeks after the last dose.

Kidney

Use with Caution

Patients with kidney disease should use Hamsyl Injection with caution. It is important that patients with kidney disease monitor their kidney function closely while taking Hamsyl 3750 IU and report any unusual symptoms or changes in kidney function to their doctor or health care professional. The dose of Hamsyl 3750 IU Injection may need to be adjusted in patients with kidney disease.

Liver

Use with Caution

The use of Hamsyl 3750 IU Injection should be used with caution in patients with liver disease. It is important that patients with liver disease monitor their liver function closely while taking Hamsyl 3750 IU and report any unusual symptoms or changes in liver function to their doctor or health care professional. In such patients with liver disease, the dose may need to be adjusted by your doctor.