Jakavi 5 mg Tablet | 10 Tablets in 1 Strip

Introduction of Jakavi 5mg Tablet

​Jakavi 5 mg Tablet is a Janus kinase inhibitor. It is used for the treatment of intermediate or high-risk Myelofibrosis (an uncommon type of bone marrow cancer) and Polycythemia vera (a blood disorder characterized by an overproduction of red blood cells). A blood cell count must be performed before initiating therapy withJakavi 5 mg Tablet. Jakavi 5 mg Tablet is not recommended for use in patients under 12 years of age safety and efficacy are not established.

The most common side effects are bruising, Dizziness, headache, urinary tract infections, weight gain, and flatulence. These side effects may be temporary and usually, go away on their own. However, if they persist or worsen, consult your doctor. This medicine may decrease the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

This Jakavi 5 mg Tablet is not recommended for during pregnancy or while planning to become pregnant, or while breastfeeding as it may cause birth defects and abortion. Please consult your doctor before taking Jakavi 5 mg. Please make sure to inform your doctor, if you have any signs of infection or if you have any pre-existing disease such as kidney or liver disease or any other health problems before taking this medicine. Additionally, let your doctor know about any other medications you are taking as they may interact with Jakavi 5 mg. Regular blood tests will be conducted to monitor the number of blood cells, sugar levels and cholesterol levels in your blood.

Jakavi 5 mg Tablet can be taken with or without food or as directed by your doctor. Take it at the same time each day. Swallow the tablet whole with a full glass of water. Do not crush, chew, or open the tablet. If you forget to take a dose, make up for it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

Uses of Jakavi 5mg Tablet

​​Polycythemia Vera: Jakavi 5 mg Tablet is used in the treatment of polycythemia vera is a rare blood disorder in which the body produces too many red blood cells. The excess red blood cells can cause the blood to become thick and sticky, making it harder to flow through the vessels. This can lead to a number of complications, including an increased risk of blood clots that can cause a heart attack or stroke.

​​Chronic idiopathic myelofibrosis: Jakavi 5 mg Tablet is used in the treatment of chronic idiopathic myelofibrosis (also called primary myelofibrosis) is a type of bone marrow disease in which the bone marrow is replaced by scar tissue, resulting in a decrease in the production of blood cells. The scar tissue can also lead to the accumulation of excess fluid in the abdomen (ascites) and the accumulation of fat cells in the liver and spleen.

Benefits of Jakavi 5mg Tablet

Jakavi 5 mg Tablet can be effective in reducing symptoms associated with myelofibrosis, such as fatigue, enlarged spleen, and uncontrolled bleeding.

Jakavi 5 mg may improve the overall quality of life and reduce the symptoms of myelofibrosis.

Jakavi 5 mg Tablet has been shown to reduce bone marrow fibrosis (scarring) in those with myelofibrosis.

Jakavi 5 mg Tablet prevent cancer in those with myelofibrosis and help to prevent the progression of myelofibrosis to acute myeloid leukaemia (AML).

Side Effects of Jakavi 5mg Tablet

​​Like all medication, Jakavi 5 mg Tablet may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.

Most Common Side Effects of Jakavi 5mg Tablet

• Headache
• dizziness
• Weight gain
• High blood pressure
• High cholesterol
• Flatulence
• Abnormal liver function tests
• Difficulty in breathing
• Constipation
  

Common Side Effects of Jakavi 5mg Tablet

• Decrease in red blood cells
• Infection
  

How to Use Jakavi 5mg Tablet?

​​Jakavi 5 mg Tablet may be taken with or without food. Take it at the same time each day. Swallow the tablet whole with a full glass of water. Do not crush, chew, or open the tablet. If you forget to take a dose, make up for it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.

How Jakavi 5mg Tablet Works?

Jakavi 5 mg Tablet belongs to the class of drugs known as Janus kinase inhibitors (JAK). The action of {Product_name_o} neis based on inhibiting the activity of certain proteins called JAKs, which play a role in signalling pathways that regulate the production of certain proteins in the body. By inhibiting these proteins, Jakavi 5 mg may help reduce inflammation and improve symptoms in certain diseases such as myelofibrosis and polycythemia vera.

Safety Advices Jakavi 5mg Tablet

Pregnancy

Unsafe

Liver

Use with Caution

Kidney

Use with Caution

Alcohol

Unsafe

Breastfeeding

Unsafe

Driving

Unsafe

References

1. Ruxolitinib 5 Mg, 10 Mg, 15 Mg And 20 Mg Tablets, Novartis Healthcare Pvt. Ltd, Product Leaflet 

2. Jakafi, (ruxolitinib) Tablets, For Oral Use, Incyte Corporation, Product Leaflet 

3.Jakavi, (ruxolitinib), Novartis, Avaliable Form

4. Jakafi Prescribing Information, Drugs.com, Avaliable Form

5. Jakafi- Ruxolitinib Tablet, Daily Med.com, Avaliable Form 

6. Ruxolitinib, Medlineplus, Avaliable Form