Tysabri 300 mg Injection | 15ml in 1 vial

Introduction of Tysabri 300 mg Injection

Tysabri 300 mg Injection is a monoclonal antibody. It is used to treat a disease of the central nervous system called multiple sclerosis and an inflammatory bowel condition known as Crohn's disease in adults. This medicine affects the actions of the body's immune system and destroys only certain cells in the body. This may help to protect healthy cells from damage. It is not known if Tysabri 300 mg is safe and effective in children under 18 years of age.

This medicine may cause some adverse effects including Headache, feeling tired, urinary tract infection, joint pain, lung infection, depression, pain in your arms or legs, diarrhoea, vaginitis, rash, nose and throat infections, nausea, and stomach-area pain. If you experience any side effect that bothers you or does not go away, tell your doctor.

Before receiving this Tysabri 300 mg, if you have a medical condition that can weaken your immune system, such as HIV infection or AIDS, leukaemia or lymphoma, organ transplant, or others, or if you have any new or worsening medical problems that have lasted several days.If you are pregnant or plan to become pregnant. In pregnancy Tysabri 300 mg Injection may cause low platelets, and in some cases also low red blood cells (anaemia), please make sure to take advice from your doctor before receiving Tysabri 300 mg Injection. Additionally, inform your doctor. If you are breastfeeding or plan to breastfeed. Tysabri 300 mg Injection can pass into your breast milk. Talk to your doctor about the best way to feed your baby while you receive Tysabri 300 mg. Inform all of the medicines and supplements you take, especially medicines that can weaken your immune system. If you are not sure, ask your doctor.

Tysabri 300 mg Injection may increase the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML). Patients taking Tysabri should be closely monitored for signs of PML and should discuss the risks and benefits of the medication with their doctor.

​​Tysabri 300 mg is administered intravenously at a hospital or clinic setting by a doctor or nurse. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You might be prescribed certain other medicine as a part of your treatment. You should take this medicine for as long as it is prescribed for you.​​

Uses of Tysabri 300 mg Injection

Multiple sclerosis: Tysabri 300 mg Injection is used in the treatment of multiple sclerosis (MS) is a disease of the brain and spinal cord in which a person’s immune system attacks the protective sheath (called myelin) of the nerves. This leads to symptoms such as vision loss, pain, fatigue and improper coordination.

Crohn’s disease: Tysabri 300 mg Injection is used in the treatment of Crohn's disease is a chronic inflammatory bowel disease (IBD) that can affect any part of the digestive tract, from the mouth to the anus. In Crohn's disease, the immune system attacks the lining of the digestive tract, leading to inflammation, ulcers, and thickening of the bowel wall.

Benefits of Tysabri 300 mg Injection

Multiple sclerosis (MS) is a disease of the brain and spinal cord in which a person’s immune system attacks the protective sheath (called myelin) of the nerves. This leads to symptoms such as vision loss, pain, fatigue and improper coordination. Tysabri 300mg Injection helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged nerves, prevents further damage and stabilises your immune system. It improves muscle strength and helps the patients to walk better. This makes the patients more confident and enhances their quality of life.

Crohn's disease is a chronic inflammatory bowel disease (IBD) that can affect any part of the digestive tract, from the mouth to the anus. In Crohn's disease, the immune system attacks the lining of the digestive tract, leading to inflammation, ulcers, and thickening of the bowel wall. Tysabri 300 mg Injection works by binding to certain immune cells and preventing them from crossing the blood-brain barrier or inflamed intestinal lining, thereby reducing inflammation in the affected areas.

Side Effects of Tysabri 300 mg Injection

​​​​​​​​Like all medications, Tysabri 300 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​​​

Most Common Side Effects of Tysabri 300 mg Injection

• Diarrhoea
• Vaginitis
• Rash
• Nose and throat infections
• Nausea, 
• Stomach area pain.​
  

Common Side Effects of Tysabri 300 mg Injection

• Headache
• Feeling tired 
• Urinary tract infection 
• Joint pain
• Lung infection
• Depression
• Pain in your arms or legs
  

How to Use Tysabri 300 mg Injection?

​​​Tysabri 300 mg is administered intravenously at a hospital or clinic setting by a doctor or nurse. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You might be prescribed certain other medicine as a part of your treatment. You should take this medicine for as long as it is prescribed for you.​​

How Tysabri 300 mg Injection Works?

In multiple sclerosis, the immune system attacks the myelin, a fatty substance that surrounds and protects nerve fibres in the brain and spinal cord. This leads to inflammation and damage to the myelin and nerve fibres. By preventing immune cells from crossing the blood-brain barrier, Tysabri 300 mg reduces inflammation in the central nervous system, which can help slow down the progression of the disease and reduce the frequency and severity of relapses.

In Crohn's disease, the immune system attacks the lining of the digestive tract, leading to inflammation, ulcers, and thickening of the bowel wall. By preventing immune cells from crossing the intestinal lining, Tysabri 300 mg Injection reduces inflammation in the affected areas and can help improve symptoms and reduce the need for hospitalization.

Safety Advices Tysabri 300 mg Injection

Alcohol

Unsafe

Pregnancy

Unsafe

Breastfeeding

Unsafe

Driving

Unsafe

Kidney

Use with Caution

Liver

Use with Caution

References

1. Tysabri 300 Mg Concentrate For Solution For Infusion, Biogen Netherlands B.v, Product Leaflet

2. Tysabri 300mg Injection, Nexus Lifecare Pvt. Ltd, Avaliable Form

3. Tysabri (natalizumab) Injection, For Intravenous Use, Biogen Idec Inc, Product Leaflet

4. Natalizumab, Drugs.com, Avaliable Form