Zubidox 10 mg Injection | 5 ml in 1 Vial

Introduction of Zubidox 10 mg Injection

​Zubidox 10 mg Injection is used with other medicines to treat certain types of bladder, breast, lung, stomach, and ovarian cancer, Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (cancer that originates in the cells of the immune system), and certain types of leukaemia (cancer of the white blood cells), including acute lymphocytic leukaemia (ALL) and acute myeloid leukaemia (AML). Zubidox 10 mg Injection is also used alone or combined with other medicines to treat certain types of thyroid cancer and certain types of soft tissue or bone sarcoma (cancer that forms in muscles and bones). It is also used to treat neuroblastoma (cancer that starts in nerve cells and occurs mainly in children) and Wilms tumour (a type of kidney cancer that occurs in children). Zubidox 10 mg Injection belongs to a class of drugs called anthracyclines. It works by slowing or stopping the growth of cancer cells in your body.

Zubidox 10 mg Injection may cause some adverse effects including vomiting, allergic reaction, nausea, mouth soreness, and hair loss. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells. It is important to talk to your doctor about the potential risks and benefits of taking Zubidox 10 mg Injection. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.

​Before taking Zubidox 10 mg Injection, inform your doctor about your past and present medical history, if you have any pre-existing disease such as liver and kidney or blood disorders, any infections or any other medical complications. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Zubidox 10 mg Injection is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

​​​​​Zubidox 10 mg Injection is administered intravenously at a hospital or clinic setting by a doctor or nurse. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You might be prescribed certain other medicine as a part of your treatment. You should take this medicine for as long as it is prescribed for you.​

​Zubidox 10 mg Injection should not be used in patients with severe liver disease, severe heart problems, very low blood cell counts caused by prior chemotherapy, or if you recently had a heart attack.​

Uses of Zubidox 10 mg Injection

​Breast cancer: Zubidox 10 mg Injection is used to treat Breast cancer is a type of cancer that affects the cells in the breast tissue. It is the second most common type of cancer in women and is often characterized by the presence of a tumour or lump in the breast.

​Bladder cancer: Zubidox 10 mg Injection is used in the treatment of Bladder cancer is a type of cancer that affects the bladder, which is a muscular organ in the lower abdomen that stores urine. It is most common in men over the age of 50 and is usually found in the cells lining the inside of the bladder.

​Kaposi's sarcoma: Zubidox 10 mg Injection is used in the treatment of Kaposi's sarcoma is a type of cancer that can affect the skin, mouth, and internal organs. It is caused by a virus called human herpesvirus 8 (HHV-8), which is also known as Kaposi's sarcoma-associated herpesvirus (KSHV). Kaposi's sarcoma is more common in people with compromised immune systems, such as people with HIV/AIDS or organ transplant recipients taking immunosuppressive drugs.

​Hodgkin's lymphoma: Zubidox 10 mg Injection is used in the treatment of Hodgkin's lymphoma, also known as Hodgkin's disease, which is a type of cancer that affects the lymphatic system.

​Acute lymphocytic leukaemia(ALL): Zubidox 10 mg Injection is used in the treatment of Acute lymphocytic leukaemia a type of cancer that affects the blood and bone marrow.

Benefits of Zubidox 10 mg Injection

Zubidox 10 mg Injection may help to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Zubidox 10 mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.​

Side Effects of Zubidox 10 mg Injection

​Zubidox 10 mg Injection may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​

Most Common Side Effects of Zubidox 10 mg Injection

• Hair loss
• Bone marrow suppression
• Vomiting
• Rash
• Inflammation of the mouth.

Common Side Effects of Zubidox 10 mg Injection

• Allergic reactions such as anaphylaxis
• Heart damage
• Tissue damage at the site of injection
• Radiation recall

How to Use Zubidox 10 mg Injection?

​Zubidox 10 mg Injection is given intravenously (IV), administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of this medicine will depend on the clinical condition of the patient's age and medical history, and other factors. It is important to follow your doctor's instructions carefully when using this medication. Do not self-administered.

How Zubidox 10 mg Injection Works?

​Zubidox 10 mg Injection interacts with DNA by inhibition and the intercalation of the macromolecular biosynthesis. Zubidox 10 mg Injection stabilizes the topoisomerase II complex after it breaks the chain of the DNA needed for replication. Zubidox 10 mg prevents the double helix DNA to get sealed and it gradually stops the replication process. Zubidox 10 mg may also increase quinone-type free radical production, hence contributing to its cytotoxicity.​

Safety Advices Zubidox 10 mg Injection

Alcohol

Unsafe

Driving

Unsafe

Pregnancy

Unsafe

Liver

Use with Caution

Kidney

Safe

Breastfeeding

Unsafe

References

1. Pfizer Injectables Adds Doxorubicin Hydrochloride Injection, Usp To Its Portfolio Of Off-patent Oncology Products, Pfizer Inc, Avaliable form

2. Adriamycin (doxorubicin Hcl) For Injection, Usp, Manufactured, Bedford Laboratories, Product Monograph 

3. Doxorubicin, Cancer Research Uk, Available Form

4. Doxorubicin (rx), Medscape.com, Avaliable Form

5. Doxorubicin, MedlinePlus, Available Form