Zumustin 100 mg Injection | 100 mg in 1 Vial

Introduction of Zumustin 100 mg Injection

Zumustin 100 mg Injection is an anticancer medicine used for the treatment of various cancers. Zumustin 100 mg Injection is primarily used in adult patients with chronic lymphocytic leukaemia, (a cancer of the white blood cells). Additionally Zumustin 100 mg Injection is used in combination with other anticancer medications to treat a specific type of non-Hodgkin's lymphoma, (cancer that starts in a type of white blood cell responsible for fighting infections). It works by destroying existing cancer cells and impeding the growth of new ones.

Zumustin 100 mg Injection may cause certain adverse effects, including nausea, vomiting, diarrhoea, heartburn, constipation, stomach pain or swelling, sores or white patches in the mouth, dry mouth, bad taste in the mouth or difficulty tasting food, loss of appetite, weight loss, headache, anxiety, depression, difficulty falling asleep or staying asleep, back, bone, joint, arm or leg pain, dry skin, sweating, and night sweats. If you experience any of these side effects and they persist or become troublesome, it is recommended to inform your doctor immediately for further advice.

Zumustin 100 mg Injection should not be used if you have a known allergy or hypersensitivity to Zumustin 100 mg or any of its components. You should inform your doctor if you are using any prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products, Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may interact with Zumustin 100 mg, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

It is essential to inform your doctor before taking Zumustin 100 mg Injection if you have a history of viral infections, liver infections, hepatitis B virus infection, tuberculosis (T.B.), herpes zoster, or kidney or liver disease. If you are pregnant or planning to become pregnant or to father a child, you should inform your doctor. It is not recommended to become pregnant while receiving Zumustin 100 mg, and you and your partner should use birth control during treatment and for three months afterwards. It is advisable to discuss birth control methods with your doctor that will work best for you. If you or your partner becomes pregnant while receiving Zumustin 100 mg, please contact your doctor immediately, as it may harm the fetus.

Zumustin 100 mg Injection should be given intravenously. Your doctor will determine the appropriate dosage and frequency of administration based on the severity of your condition, which may be subject to change. It is important to follow your doctor's instructions for taking Zumustin 100 mg, as improper or excessive intake may lead to severe adverse effects. Although it may take several weeks or months to observe the benefits of the medication, it is essential not to discontinue treatment unless your doctor tells you to.

Uses of Zumustin 100 mg Injection

Chronic Lymphocytic Leukemia (CLL): Zumustin 100 mg Injection is used for the treatment of chronic lymphocytic leukaemia, which is a type of cancer that affects the blood and bone marrow, where blood cells are produced. Chronic lymphocytic leukaemia is characterized by the accumulation of abnormal lymphocytes (a type of white blood cell) in the bone marrow, blood, and lymphatic system.

Non-Hodgkin Lymphoma (NHL): Zumustin 100 mg Injection used in the treatment of Non-Hodgkin lymphoma (NHL) is a cancer of the lymphatic system, which can cause various symptoms including swollen lymph nodes, fever, night sweats, weight loss, and fatigue.

Benefits of Zumustin 100 mg Injection

Zumustin 100 mg Injection is used for treating a variety of cancers, such as non-Hodgkin's lymphoma and chronic lymphocytic leukaemia. It shows various potential benefits such as causing fewer side effects compared to other anticancer drugs. Moreover, Zumustin 100 mg can help improve the quality of life by decreasing cancer symptoms and slowing down the progression of the disease. Zumustin 100 mg Injection has the potential to enhance the quality of life for cancer patients by reducing symptoms and slowing disease progression.

Side Effects of Zumustin 100 mg Injection

​​​​​​​​Like all medications, Zumustin 100 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​

Most Common Side Effects of Zumustin 100 mg Injection

• Low Count of Blood Cells
• Vomiting
• Nausea
• High or Low Blood Pressure
• Hair Loss
• Constipation
• Fever
• Infection
  

Common Side Effects of Zumustin 100 mg Injection

• Liver Related Issues
• Allergic Reactions
• Tumor Lysis Syndrome
  

How to Use Zumustin 100 mg Injection?

Zumustin 100 mg Injection should be given intravenously. Your doctor will determine the appropriate dosage and frequency of administration based on the severity of your condition, which may be subject to change. It is important to follow your doctor's instructions for taking Zumustin 100 mg, as improper or excessive intake may lead to severe adverse effects. Although it may take several weeks or months to observe the benefits of the medication, it is essential not to discontinue treatment unless your doctor tells you to.

How Zumustin 100 mg Injection Works?

Zumustin 100 mg Injection works by damaging the DNA in cancer cells, which prevents them from multiplying and dividing. The Zumustin 100 mg Injection also disrupts the cancer cell's ability to repair damaged DNA, which ultimately leads to the death of cancer cells.

Safety Advices Zumustin 100 mg Injection

Kidney

Use with Caution

Breastfeeding

Unsafe

Driving

Unsafe

Liver

Use with Caution

Alcohol

Unsafe

Pregnancy

Unsafe

References

1. Bendamustine Injection, MedlinePlus, Avaliable Form 

2. Bendamustine Injection Prescribing Information, Drugs.com, Avaliable From 

3. Treanda, (bendamustine Hydrochloride) For Injection, For Intravenous Infusion, Cephalon, Inc, Product Leaflet 

4. Bendamustine Lu Bendamustine Hydrochloride 100 Mg Powder For Injection Vial, Therapeutic Goods Administration (TGA), Avaliable Form 

5. Bendamustine 25 Mg And 100 Mg Powder For Concentrate For Solution For Infusion, S.c. Sindan-pharma, Product Monograph 

6. Ribomustin, Bendamustine Hydrochloride, Janssen-cilag (New Zealand) Ltd, [date Of Revision 12 August 2022], Product Leaflet