Actemra 162 mg PFS | 162 mg

Introduction of Actemra 162 mg Injection

Actemra 162 mg PFS is a medicine used to treat a variety of conditions including ankylosing spondylitis, rheumatoid arthritis, psoriasis, ulcerative colitis and Crohn's disease. Actemra 162 mg is a disease-modifying anti-rheumatic drug and a monoclonal antibody that works by inactivating tumour necrosis factor-alpha (TNFα). It helps reduce the swelling, pain and redness associated with several conditions and improves physical function. It is administered by injection under the skin.

Common side effects include headache, sinusitis, rash, upper respiratory infection, and injection site reactions such as pain, redness, and swelling. If you experience any of these side effects, you should talk to your doctor if they do not get better over time or if they get worse. Your doctor or health care professional may be able to give you advice on the reduction or prevention of these symptoms.

Before taking Actemra 162 mg PFS, tell your doctor if you have heart, kidney or liver problems, or if you have infections such as tuberculosis (TB) or other bacterial, fungal or viral infections. If you have a nervous system disorder, including multiple sclerosis, optic neuritis, or Guillain-Barre syndrome. All other medicines you are taking should also be told to your doctor. Women who are pregnant or breastfeeding should seek the advice of their doctor or health professional before taking this medicine.

Actemra 162 mg is given by a health care professional and should not be used by yourself. You should take it regularly at the same time each day to get maximum benefit. Take your medicine as directed by your doctor. Finish the full course of medicine even if you feel better.

Uses of Actemra 162 mg Injection

• Rheumatoid arthritis
  
• Ankylosing spondylitis
• Crohn disease
• Ulcerative colitis
• Hidradenitis suppurativa
• Juvenile idiopathic arthritis
• Plaque psoriasis
• Psoriatic arthritis
• Uveitis

Benefits of Actemra 162 mg Injection

Rheumatoid arthritis: Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints. It causes inflammation, pain, stiffness, and swelling in the joints, and can also affect other parts of the body, such as the skin, eyes, lungs, heart, and blood vessels. Actemra 162 mg helps reduce inflammation and manage the symptoms of Rheumatoid arthritis.

Ankylosing spondylitis: Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine, causing pain, stiffness, and reduced mobility. It is a form of arthritis that mainly affects the joints between the vertebrae in the spine and the sacroiliac joints where the spine connects to the pelvis. Actemra 162 mg Injection works by targeting and inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing the inflammation associated with ankylosing spondylitis, Actemra 162 mg PFS can help relieve pain, stiffness, and other symptoms of the condition.

Crohn's disease: Crohn's disease is a chronic inflammatory bowel disease (IBD) that primarily affects the gastrointestinal tract. It can cause inflammation and damage to any part of the digestive system, from the mouth to the anus. Symptoms of Crohn's disease can vary but commonly include abdominal pain, diarrhoea, weight loss, fatigue, and loss of appetite. Actemra 162 mg works by targeting and inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation in the gastrointestinal tract, Actemra 162 mg PFS can help manage the symptoms of Crohn's disease, including abdominal pain, diarrhoea, and inflammation.

Ulcerative colitis: Ulcerative colitis is a chronic inflammatory bowel disease that primarily affects the colon and rectum. Actemra 162 mg Injection can help reduce inflammation in the gastrointestinal tract and manage the symptoms of ulcerative colitis.

Hidradenitis suppurativa: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that affects the hair follicles in areas of the body with a high concentration of sweat glands, such as the armpits, groin, and buttocks. Actemra 162 mg works by targeting and inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation, Actemra 162 mg PFS can help alleviate symptoms and prevent the progression of hidradenitis suppurativa.

Juvenile idiopathic arthritis: Juvenile idiopathic arthritis (JIA) is a type of arthritis that occurs in children under the age of 16 and persists for at least six weeks. It is characterized by joint inflammation, pain, stiffness, and swelling. Actemra 162 mg PFS works by inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation in the joints, adalimumab helps manage the symptoms of Juvenile idiopathic arthritis, including pain, stiffness, and swelling.

Plaque psoriasis: Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Actemra 162 mg Injection reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Psoriatic arthritis: Psoriatic arthritis is a type of inflammatory arthritis that occurs in some individuals with psoriasis, a chronic skin condition. It causes joint pain, swelling, and stiffness, and can affect any joint in the body. Actemra 162 mg PFS works by inhibiting tumour necrosis factor (TNF), a protein involved in inflammation. By reducing inflammation in the joints, adalimumab can help manage the symptoms of psoriatic arthritis, including joint pain, stiffness, and swelling.

Uveitis: Uveitis refers to the inflammation of the uvea, which is the middle layer of the eye. It can affect various parts of the uvea, including the iris, ciliary body, and choroid. Actemra 162 mg is a tumour necrosis factor (TNF) inhibitor that helps reduce inflammation by targeting TNF, a protein involved in the immune response.

Side Effects of Actemra 162 mg Injection

​​​​​​​​​​As with all medicines, Actemra 162 mg PFS may cause side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. If they persist or you're concerned about them, tell your doctor.​

Most Common Side Effects of Actemra 162 mg Injection

• Diarrhoea
• Headache
• Throat, Nasal and Chest infections
• Skin infections
• Tiredness
• Yellow Eyes and Skin.
• Appetite loss
• Vomiting
• Darker Urine and Tarry stool
• skin rashes
• Short breathing
• Chest pain
• Coughing and Sneezing with blood and Mucus
• redness and Swelling of Skin
• painful Urination
• Weigh loss
• Changes in Frequency and Consistency of passing stool.

Common Side Effects of Actemra 162 mg Injection

• Blood Clots
• sudden shortness of Breath
• Painful Breathing
• Chest Pain
• Heavy Sweating
• Redness, Painful and Swollen limbs.

How to Use Actemra 162 mg Injection?

​​Actemra 162 mg PFS is given subcutaneously (under the skin) from any health care professional. Dosage and frequency will be decided by your doctor as per your disease condition and several other factors.​

How Actemra 162 mg Injection Works?

​Actemra 162 mg PFS works by blocking the activity of a specific protein (cytokine) called interleukin-6, which is involved in inflammatory processes in the body. Blocking this protein can reduce pain and swelling in your joints.​

Safety Advices Actemra 162 mg Injection

Breastfeeding

Safe

Kidney

Use with Caution

Alcohol

Unsafe

Pregnancy

Safe

Driving

Unsafe

Liver

Use with Caution

References

1. Actemra® (Tocilizumab) Injection, for Intravenous or Subcutaneous Use, Product Leaflet

​2. Actemra- Tocilizumab Injection, Solution, Avaliable From

3. Roactemra 20 Mg/Ml Concentrate for Solution for Infusion, Product Leaflet

4. Actemra® 20 Mg/Ml, Concentrate for Solution for Intravenous (Iv) Infusion, Product Leaflet