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Nindanib 150 mg Capsule
Nindanib 150 mg Capsule
Prescription Required
Prescription Required

Nindanib 150 mg Capsule | 10 Capsules in 1 Strip

734.40
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Glenmark Pharmaceuticals Ltd
Nintedanib 150 mg
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Introduction of Nindanib 150 mg Capsule

Nindanib 150 mg Capsule is a member of a group of drugs called tyrosine kinase inhibitors. It is used in the treatment of idiopathic pulmonary fibrosis (IPF). It helps to prevent changes in lung tissue. Nindanib 150 mg is also used to treat people with chronic (long-lasting) interstitial lung disease, where the lung fibrosis continues to progress or gets worse. Nindanib Capsule is also used to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease.

Some common side effects of Nindanib 150 mg Capsule include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor may ask you to have some blood tests to monitor your liver function. Diarrhoea is a very common side effect of this medicine and should be avoided. You should drink plenty of fluids. Tell your doctor or health care professional if you get diarrhoea.

Tell your doctor if you have a bleeding problem, liver or kidney problems, or if you are taking any medicines to treat infections before you take Nindanib 150 Capsule. Many other medications have the potential to interact with or be influenced by this drug. Therefore, it is essential to inform your healthcare team about all the medications you are currently using. Nindanib 150 mg Capsule is not recommended during pregnancy or while breast-feeding. The use of effective contraception by both men and women during treatment is important to avoid pregnancy.

Nindanib 150 mg Capsule should be taken with food, but try to take it at the same time each day to get the most benefit. The dose you need and how often you take it will be decided by your doctor. The appropriate usage of this medication varies based on the condition being treated and might be subject to change over time. It's crucial to follow your doctor or healthcare professional's guidance precisely when taking this medicine. Misuse or overconsumption can lead to severe side effects. Ceasing the medication should only be done under your doctor's direction. The effects of this medicine may not be immediately noticeable, often taking several weeks or even months before experiencing its benefits.


Uses of Nindanib 150 mg Capsule

  • Idiopathic pulmonary fibrosis
  • Interstitial lung disease
  • NSCLS (Non-small cell lung Cancer)
  • Systemic sclerosis


Benefits of Nindanib 150 mg Capsule

Idiopathic pulmonary fibrosis: Idiopathic pulmonary fibrosis is a lung disease in which lung tissue becomes thick and stiff, eventually forming scar tissue in the lungs. The scarring, or fibrosis, appears to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the first symptoms may be shortness of breath or a dry cough. Nindanib 150 mg Capsule kills or stops the growth of cancer cells and also prevents cancer cells from multiplying. It is possible that you may experience some unpleasant side effects.Discuss this together along with your physician when you have any concerns.

Interstitial lung disease: Interstitial lung disease (ILD) refers to a group of lung diseases that affect the interstitium, which is the tissue and space around the air sacs in the lungs. These conditions cause inflammation and scarring of the lung tissue, leading to difficulty in breathing. Nindanib Capsule kills or stops the growth of cancer cells and also prevents cancer cells from multiplying.You may additionally experience some unpleasant factor effects.If you've got got any concerns, please speak them together along with your doctor.

Non-small cell lung cancer (NSCLC) Non-small cell lung cancer is one of the main types of lung cancer and affects both smokers and non-smokers. Nindanib 150 mg helps treat NSCLC and can be given alone or in combination with other medicines. It is a strong and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol during this treatment and drink plenty of water to stay hydrated.

Systemic sclerosis: Systemic sclerosis, commonly known as scleroderma, is an autoimmune disease that can affect various parts of the body, including the skin and internal organs. By reducing the progression of fibrosis, Nindanib 150 Capsule may help to maintain or preserve lung function, leading to better lung capacity and potentially slowing the decline in lung function.


Side Effects of Nindanib 150 mg Capsule

Like all medicines, Nindanib 150 mg Capsule may cause side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. Tell your doctor if they persist or if you're worried about them.


Most Common Side Effects of Nindanib 150 mg Capsule

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach upset
  • ​Loss of appetite
  • Weight loss
  • Fatigue
  • Headache
  • Unhealed wound​


Common Side Effects of Nindanib 150 mg Capsule

  • Altered blood pressure
  • Liver problems (jaundice)
  • Dark brown urine
  • Yellowing of the skin
  • Lack of energy
  • Shortness of breath
  • Numbness or weakness
  • Difficulty in speech
  • Malena ( blood in stool)


How to Use Nindanib 150 mg Capsule?

Nindanib 150 mg Capsule is available in the form of oral capsules to be taken by mouth as prescribed by your doctor. The frequency and dosage of the medicine will be decided by your doctor depending on the severity of the disease and certain other factors and how your body responds to the treatment.


How Nindanib 150 mg Capsule Works?

Nindanib 150 mg Capsule is a tyrosine kinase inhibitor. Nindanib 150 Capsule works by blocking certain enzymes in the body called tyrosine kinases that are involved in the growth and spread of certain types of cells, including cancer cells and cells involved in fibrosis. By blocking these enzymes, Nindanib 150 mg helps to slow the progression of diseases such as idiopathic pulmonary fibrosis and non-small cell lung cancer. Nindanib Capsule is usually taken orally and is usually well tolerated, although some side effects such as diarrhoea, nausea and stomach pain may occur. It is important to follow your doctor's instructions and to report any side effects to your doctor.


Safety Advices Nindanib 150 mg Capsule

kidney
Kidney
Use with Caution

Nindanib 150 mg should be used with caution in patients with Kidney disease. It is important that patients with kidney disease closely monitor kidney function while taking Nindanib Capsule and report any unusual symptoms or changes in kidney function to their doctor. The dose of Nindanib 150 Capsule may need to be adjusted in patients with kidney disease.

liver
Liver
Use with Caution

Nindanib 150 mg Capsule should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Nindanib Capsule and report any unusual symptoms or changes in liver function to their doctor. The dose of Nindanib 150 Capsule may need to be adjusted in patients with liver disease.

alcohol
Alcohol
Unsafe

It is generally not recommended to drink alcohol while taking Nindanib 150 mg. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

driving
Driving
Unsafe

Nindanib 150 mg Capsule may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Nindanib 150 Capsule.

pregnancy
Pregnancy
Unsafe

Use of Nindanib 150 mg Capsule may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Nindanib 150 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

breastfeeding
Breastfeeding
Unsafe

It is not recommended to breastfeed while taking Nindanib 150 Capsule. Nindanib 150 mg Capsule may pass into breast milk and harm the infant. If you are breastfeeding and taking Nindanib 150 mg, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.


References

1. Nintib (nintedanib Capsules 100 Mg,150 Mg) To Treat Idiopathic Pulmonary Fibrosis, In Continuation Of Its Fight Against Rare Lung Diseases, Cipla Ltd. India, Product Leaflet 

2. Nintedanib Soft Gelatin Capsules, Boehringer Ingelheim India Private Limited. India, Product Leaflet 

3. Ofev (nintedanib) Capsules, For Oral Use, Boehringer Ingelheim Pharmaceuticals, Inc. USA, Available Form 

4. Nintedanib 100mg And 150mg Capsules, Ofev, Boehringer Ingelheim, Scottish Medicines Consortium, Product Leaflet 

5. Ofev 150 Mg Soft Capsules, Boehringer Ingelheim Pharma Gmbh & Co. Kg, Available Form 

6. Nintedanib, Drugs.com, Available Form

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