Actilyse 20 mg Injection
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Actilyse 20 mg Injection

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Boehringer Ingelheim India Pvt Ltd
Alteplase 20 mg

Introduction of Actilyse Injection

Actilyse 20 mg Injection is a thrombolytic medication used to treat acute ST elevation MI, Acute ischemic stroke and pulmonary embolism associated with low blood pressure and blocked central venous catheter. Actilyse 20 mg Injection induces fibrinolysis and causes the breakdown of a clot. Chemical formula of Actilyse 20 mg Injection is C2569H3928N746O781S40. Actilyse 20 mg Injection is administered as an IV ( intravenously) under medical supervision.

Uses of Actilyse Injection

  • Stroke caused by a blood clot or other obstruction in a blood vessel MI
  • Heart attack (acute myocardial infarction)
  • Blood clot in the lung (pulmonary embolism)

Benefits of Actilyse Injection

Actilyse 20 mg Injection is mainly used for acute myocardial infarction ( STEMI ) and acute ischemic stroke, Massive pulmonary embolism, and a central venous catheter. It is used as a thrombolytic drug, also known as a fibrinolytic agent. Actilyse 20 mg Injection is also used for DVT ( Deep vein thrombosis ), peripheral artery disease, pleural effusion, prosthetic valve thrombosis, peritonitis.

Side Effects of Actilyse Injection

  • Anxiety
  • Pale skin
  • Convulsion
  • Cough
  • Dilated neck veins
  • Extreme fatigue
  • Muscle spasm

Most Common Side Effects of Actilyse Injection

  • Bleeding
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Nose bleeding
  • Paralysis
  • Prolonged bleeding from cuts
  • Red or dark brown urine
  • Difficulty in breathing
  • Difficulty in swallowing

Common Side Effects of Actilyse Injection

  • Tachycardia ( fast heartbeat )
  • Fainting
  • Slurred speech
  • Sudden loss of consciousness
  • Altered sensorium
  • Respiratory distress
  • Vision changes
  • Shallow/ Rapid breathing

How to Use Actilyse Injection?

Actilyse 20 mg Injection is administered as an infusion into a vein ( as an intravenous injection). It is usually given within 3 hours after the stroke or Heart attack's first sign.

How Actilyse Injection Works?

Actilyse 20 mg Injection was the first recombinant tissue type plasminogen activator that binds to fibrin in the thrombus. Entrapped plasminogen is converted to plasmin by the plasminogen activator. Plasmin conversion initiates local fibrinolysis.


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