Plasbumin 20% Injection | 100 ml in 1 vial

Introduction of Plasbumin Injection

Plasbumin 20% Injection is a sterile, liquid preparation of albumin derived from human plasma. Plasbumin Injection is used to treat loss of blood volume. It is indicated for conditions such as hypovolemia, hypoalbuminaemia, acute nephrosis and liver failure. Plasbumin 20% is used to replace blood volume loss resulting from excessive trauma, bleeding, severe burns or injury, by maintaining the oncotic pressure or colloid osmotic pressure of the circulating blood volume.

Patients with a history of allergy to Plasbumin and those with cardiac failure, pulmonary oedema, or severe anaemia should not use this Plasbumin Injection. 

The use of Plasbumin 20% may have an impact on blood pressure and sodium levels. Plasbumin Injection may cause an elevation in blood pressure because of its volume-expanding effects and also a rise in sodium levels as it is made from human blood plasma, which contains sodium. However, the effect on blood pressure and sodium levels may vary depending on the patient's specific medical condition and reaction to the treatment. Therefore, it is important to closely monitor blood pressure and sodium levels when receiving Plasbumin 20.

Uses of Plasbumin Injection

Hypovolemia: Plasbumin 20% Injection is used to treat hypovolemia is a condition characterized by low blood volume, which can be caused by various factors such as blood loss, dehydration, or excessive fluid loss.

Hypoalbuminaemia: Plasbumin Injection is used for the treatment of hypoalbuminemia, which is a condition characterized by low levels of albumin in the blood. This can occur as a result of conditions such as liver disease, kidney disease, malnutrition, and chronic inflammation.

Acute Nephrosis: Plasbumin 20% is used in the treatment of acute nephrosis a medical condition characterized by inflammation and swelling of the kidneys.

Liver Failure: Plasbumin 20 is used in the treatment of liver failure.

Benefits of Plasbumin Injection

Plasbumin 20% can be utilized as a volume expander to increase blood volume in cases of hypovolemia, which can occur as a result of shock, burns, and liver disease.

Plasbumin can be utilized to treat hypoalbuminemia, a condition characterized by low levels of albumin in the blood, seen in patients suffering from liver disease, kidney disease, and other medical conditions

Plasbumin 20% Injection can be employed to decrease oedema by increasing the volume of albumin in the blood and by drawing fluid back into the blood vessels.

Plasbumin Injection can be used to offer extra protein and other vital nutrients to patients who are malnourished or have nutritional deficiencies.

Side Effects of Plasbumin Injection

​​​​​Like all medications, Plasbumin Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​

Most Common Side Effects of Plasbumin Injection

• Mild hypotension
• Flushing
• Urticaria
• Fever
• Nausea

Common Side Effects of Plasbumin Injection

• Anaphylaxis

How to Use Plasbumin Injection?

Plasbumin is administered by a healthcare professional or nurse in a hospital or clinic setting. The specific dosing and administration of the Plasbumin Injection will be determined by the patient's clinical condition, age, medical history, and other factors. It is important to note that this Plasbumin Injection should not be self-administered, and it is important to follow the instructions of the healthcare professional administering the Plasbumin 20%.

How Plasbumin Injection Works?

Plasbumin 20% Injection is a solution that is intended for intravenous infusion, Plasbumin 20 is made up of human albumin, a protein that is naturally present in the blood. Plasbumin Injection works by replacing the loss of blood or body fluids that may occur due to excessive bleeding, surgeries, or kidney dialysis.

Safety Advices Plasbumin Injection

Alcohol

Unsafe

Breastfeeding

Use with Caution

Pregnancy

Safe

Driving

Safe

Kidney

Use with Caution

Liver

Use with Caution

References

1. Albumex 20 (20%) solution for infusion, CSL Behring (Australia) Pty Ltd, Product Leaflet

2. Albumex (Human Albumin solutions), Author /Reviewer: Consultant Haematologist, Scientist in Charge Transfusion Medicine, KEMH, Australia, Product Monograph 

3. Human Albumin Biotest 5%,20%, Paviour Pharmaceuticals (P) Ltd: India. Available form 

4. Human Albumin Baxalta 200 G/l Solution For Infusion, Baxter AG Industriestrasse 67 A-1221 Vienna, Austria, Product Leaflet

5. Albumin (Human) 20%, Drugs.com, Available form

6. Albumin (Human) 5%, OCTAPHARMA Pharmazeutika, Product Leaflet

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