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Actilyse 50 mg Injection
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Actilyse 50 mg Injection

1 Vial

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47000.00
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Boehringer Ingelheim India Pvt Ltd
Alteplase 50 mg

Introduction of Actilyse Injection

Actilyse 50 mg Injection is a thrombolytic agent or clot buster. Actilyse Injection is used to dissolve blood clots that have formed in the blood vessels, particularly in the heart or brain. Actilyse 50 is used to treat conditions such as heart attack, stroke, and pulmonary embolism (a blockage in the lung's blood vessels).

Actilyse 50 Injection should not be used in people with active bleeding or a history of bleeding disorders. It is important to carefully consider the risks and benefits of Actilyse before starting treatment.

Actilyse Injection is given intravenously (IV), administered by a healthcare professional in a hospital or clinic setting. The exact dosing and schedule will be determined by the healthcare professional based on the patient's condition.


Uses of Actilyse Injection

Acute Myocardial Infraction: Actilyse Injection  is used to treat acute myocardial infarction, also known as a heart attack. It works by breaking down blood clots that are blocking the blood flow to the heart. If you experiencing symptoms of a heart attack, such as chest pain, shortness of breath, or discomfort in the upper body, it is important to seek medical attention immediately.

Pulmonary Embolism: Actilyse 50 mg Injection is used to treat pulmonary embolism, which is a condition in which a blood clot in the arteries of the lungs. If you experiencing any symptoms of Pulmonary embolism. it is important to seek medical attention immediately.

Acute Ischemic Stroke: Actilyse 50 Injection is used to treat acute ischemic stroke, which is a type of stroke that occurs when a blood clot blocks the blood flow to the brain. it works by breaking down blood clots that are blocking the blood flow to the brain. If you experiencing symptoms of a stroke, such as sudden weakness or numbness on one side of the body, difficulty speaking or understanding speech or vision loss in one eye, it is important to seek medical attention immediately.


Benefits of Actilyse Injection

Actilyse 50 Injection can improve blood flow to the affected area or reduce the damage caused by a stroke or heart attack.

Actilyse can help to reduce the risk of complications such as brain damage, heart failure, and other serious conditions that can result from a stroke or heart attack.

Actilyse Injection can improve a person's quality of life and increase their chances of making a full recovery.


Side Effects of Actilyse Injection

Like all medications, Actilyse 50 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.


Most Common Side Effects of Actilyse Injection

  • Bleeding
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Nose bleeding
  • Paralysis
  • ​Anxiety
  • Pale skin
  • Convulsion
  • Cough
  • Dilated neck veins
  • Extreme fatigue
  • Muscle spasm
  • Prolonged bleeding from cuts
  • Red or dark brown urine
  • Difficulty in breathing
  • Difficulty in swallowing


Common Side Effects of Actilyse Injection

  • Tachycardia ( fast heartbeat )
  • Fainting
  • Slurred speech
  • Sudden loss of consciousness
  • Altered sensorium
  • Respiratory distress
  • Vision changes
  • Shallow/ Rapid breathing


How to Use Actilyse Injection?

Actilyse Injection is administered by a healthcare provider in a hospital or clinic setting. It is usually given as an intravenous (IV) injection or infusion. The specific dosing and administration of Actilyse 50 will depend on the clinical condition of the patient's age and medical history, and other factors.

Actilyse 50 mg Injection should be given over a period of time, usually 60 minutes for a stroke and 90 minutes for a heart attack. Closely monitor the patient's blood pressure and other vital signs during the infusion. It is important to follow your doctor's instructions carefully when using this medication.


How Actilyse Injection Works?

Actilyse 50 mg Injection  is a thrombolytic agent. It activates plasminogen, which then breaks down the blood clots. Actilyse 50 Injection helps to improve blood flow and can reduce the risk of damage to the brain or other organs due to a lack of blood flow.


Safety Advices Actilyse Injection

liver
Liver
Use with Caution

Actilyse 50 should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Actilyse 50 Injection and report any unusual symptoms or changes in liver function to their doctor. The dose of Actilyse may need to be adjusted in patients with liver disease.

kidney
Kidney
Use with Caution

Actilyse 50 Injection should be used with caution in patients with Kidney disease. It is important that patients with kidney disease closely monitor kidney function while taking Actilyse 50 and report any unusual symptoms or changes in kidney function to their doctor. The dose of Actilyse may need to be adjusted in patients with kidney disease.

pregnancy
Pregnancy
Unsafe

Use of Actilyse 50 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Actilyse 50 mg Injection during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

driving
Driving
Safe

Actilyse 50 mg Injection is unlikely to affect your ability to drive or operate machinery. If you experience any side effects while taking Actilyse Injection such as dizziness or drowsiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.

breastfeeding
Breastfeeding
Unsafe

It is not recommended to breastfeed while taking Actilyse. Actilyse Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Actilyse 50, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

alcohol
Alcohol
Unsafe

It is generally not recommended to drink alcohol while taking Actilyse 50 mg Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.


References

1. Activase (alteplase) For Injection, For Intravenous Use,genentech, Inc. South San Francisco, Product Leaflet 

2. Actilyse Powder And Solvent For Solution For Injection And Infusion Of 10 Mg, 20 Mg And 50 Mg, Boehringer Ingelheim Pharma Gmbh & Co. Kg, Product Monograph 

3. Activase Alteplase 50mg For Intravenous Use,(USA), Available Form 

4. Alteplase, Drugs.com, Available Form 

5. Actilyse Injection With Diluent Alteplase, Rch, Boehringer Ingelheim (n.z.) Limited, Available Form

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