Adcov 50 mg Injection
50 mg in 1 Vial
(Inclusive of all taxes)
Introduction of Adcov 50 mg Injection
Adcov 50 mg Injection is used to protect against the toxic effects of chemotherapy agents such as methotrexate and treat an overdose of anticancer medicines. Adcov 50 mg Injection is used in the treatment of megaloblastic anaemia due to folic acid deficiency, when oral therapy is not possible. Adcov 50 mg Injection is also combined with 5-fluorouracil to treat advanced colorectal cancer. Adcov 50 mg should not be mixed with the same infusion as 5-fluorouracil because a precipitate may form.
This medicine may cause some adverse effects such as Nausea, Urticaria, Sleeplessness, Uneasiness, Fever, Redness, Abdominal pain, Diarrhoea, and Vomiting are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in the blood.
Before taking this medicine, you should inform if you have any pre-existing disease like seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To ensure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.
Adcov 50 mg Injection is usually administered by a healthcare professional in a hospital or clinic setting. The exact dosing and schedule will be determined by the healthcare professional based on the patient's condition. It is important to follow the doctor's instructions for receiving Adcov 50 mg and to report any side effects or concerns to the doctor.
Uses of Adcov 50 mg Injection
Leucovorin Rescue After High-Dose Methotrexate Therapy: Adcov 50 mg Injection is used to rescue or protect normal cells from the toxic effects of a high dose of methotrexate. It will reduce the risk of certain long-term side effects, such as liver damage and kidney damage.
Megaloblastic anaemia: Adcov 50 mg Injection is used to treat megaloblastic anaemia, a type of anaemia with a lower than the normal number of red blood cells, caused by a deficiency of folic acid, characterized by fatigue, shortness of breath, and pale skin.
Colorectal Cancer: Adcov 50 mg Injection used to treat colorectal cancer, which is cancer that affects the colon or rectum.
Folic acid antagonist overdose: Adcov 50 mg Injection diminishes the toxicity and counteracts the effects of overdosage of folic acid antagonists.
Benefits of Adcov 50 mg Injection
Adcov 50 mg Injection can reduce serious blood cell disorders symptoms like anaemia, neutropenia and thrombocytopenia, which is occurred as a side effect of some drugs like methotrexate, pyrimethamine, and trimethoprim.
Adcov 50 mg Injection can help to decrease the side effects of chemotherapy drugs, such as nausea, vomiting, and diarrhoea, by protecting normal cells from the toxic effects of chemotherapy.
Adcov 50 mg may help to increase the effectiveness of chemotherapy drugs by allowing them to work more effectively against cancer.
Adcov 50 mg Injection can help to improve the quality of life for cancer patients by reducing the side effects of chemotherapy and potentially increasing the effectiveness of cancer treatment.
Side Effects of Adcov 50 mg Injection
Like all medications, Adcov 50 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
Most Common Side Effects of Adcov 50 mg Injection
- Nausea
- Urticaria
- Sleeplessness
- Uneasiness
- Fever
- Redness
- Abdominal pain
- Diarrhoea
- Vomiting
Common Side Effects of Adcov 50 mg Injection
- Breathing difficulty
- Dizziness
- Severe allergic reaction
- Swelling all over the body
How to Use Adcov 50 mg Injection?
Adcov 50 mg Injection is given intravenously (IV) or intramuscular (IM) administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of Adcov 50 mg will depend on the clinical condition of the patient's age and medical history, and other factors. It is important to follow your doctor's instructions carefully when using this medication.
How Adcov 50 mg Injection Works?
Adcov 50 mg Injection also known as folinic acid. Adco works by enhancing the effectiveness of certain chemotherapy drugs, such as 5-fluorouracil and methotrexate. Adcov 50 mg helps to convert these chemotherapy drugs into their active form, which allows them to target and kill cancer cells.
Safety Advices Adcov 50 mg Injection
Liver
Use with CautionAdcov 50 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Adcov 50 mg and report any unusual symptoms or changes in liver function to their doctor. The dose of Adcov 50 mg may need to be adjusted in patients with liver disease.
Breastfeeding
UnsafeIt is not recommended to breastfeed while taking Adco. Adcov 50 mg may pass into breast milk and harm the infant. If you are breastfeeding and taking Adcov 50 mg Injection, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.
Alcohol
UnsafeIt is generally not recommended to drink alcohol while taking Adcov 50 mg Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.
Pregnancy
UnsafeUse of Adcov 50 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Adcov 50 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.
Driving
SafeAdcov 50 mg Injection is unlikely to affect your ability to drive or operate machinery. If you experience any side effects while taking Adcov 50 mg such as dizziness or drowsiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.
Kidney
Use with Cautionpatients with kidney disease should closely monitor kidney function while taking Adcov 50 mg Injection and report any unusual symptoms or changes in kidney function to their physician. The dose of Adcov 50 mg should be used with caution in patients with kidney disease. It is important to adjust the dose in patients with kidney disease.
References
1. Calcium Folinate 10 Mg/ml Injection, [Date Of Last Revision: 17 May 2021]. Available Form, Online
2. Leucovorin Calcium Injection, Leucovorin (as Leucovorin Calcium), Generic Medical Partners Inc. Toronto, Ontario, Canada, Product Leaflet
3. Dbl Leucovorin Calcium 15 Mg/2 Ml, 50 Mg/5 Ml Or 300 Mg/30 Ml Solution For Injection, Pfizer New Zealand Limited [date Of Revision 13 May 2022], Product Monograph
4. Leucovorin Calcium, Avalibale Form
5. Leucovorin Calcium Injection, Dailymed, Available Form
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