Introduction of Shilstine 50 mg Injection

• Shilstine 50 mg Injection is used to protect against the toxic effects of chemotherapy agents such as methotrexate and treat an overdose of anticancer medicines. Shilstine Injection is used in the treatment of megaloblastic anemia due to folic acid deficiency when oral therapy is not possible. Calcium Leucovorin 50 mg Injection is also combined with 5-fluorouracil to treat advanced colorectal cancer. Shilstine 50 mg should not be mixed with the same infusion as 5-fluorouracil because a precipitate may form.

  
  

  This medicine may cause some adverse effects such as nausea, urticaria, sleeplessness, uneasiness, fever, redness, abdominal pain, diarrhea, and vomiting, which are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in the blood.

  
  

  Before taking this medicine, you should inform us if you have any pre-existing diseases like seizures or liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To ensure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.
  
  Shilstine Injection is usually administered by a healthcare professional in a hospital or clinic setting. The exact dosing and schedule will be determined by the healthcare professional based on the patient's condition. It is important to follow the doctor's instructions for receiving Shilstine Prefilled Syringe and to report any side effects or concerns to the doctor.

Uses of Shilstine 50 mg Injection

• Leucovorin Rescue After High-Dose Methotrexate Therapy: Calcium Leucovorin 50 mg Injection is used to rescue or protect normal cells from the toxic effects of a high dose of methotrexate. It will reduce the risk of certain long-term side effects, such as liver damage and kidney damage.
  
  Megaloblastic anemia: Leucovorin Rescue Injection is used to treat megaloblastic anemia, a type of anemia with a lower than normal number of red blood cells, caused by a deficiency of folic acid, characterized by fatigue, shortness of breath, and pale skin.
  
  Colorectal Cancer: Shilstine 50 mg Injection is used to treat colorectal cancer, which is cancer that affects the colon or rectum.
  
  Folic acid antagonist overdose: Shilstine Injection diminishes the toxicity and counteracts the effects of overdosage of folic acid antagonists.
  

Benefits of Shilstine 50 mg Injection

• Leucovorin Rescue Injection can reduce serious blood cell disorder symptoms like anemia, neutropenia, and thrombocytopenia, which occur as a side effect of some drugs like methotrexate, pyrimethamine, and trimethoprim.
  
  Calcium Leucovorin 50 mg Injection can help to decrease the side effects of chemotherapy drugs, such as nausea, vomiting, and diarrhea, by protecting normal cells from the toxic effects of chemotherapy.
  
  Shilstine 50 mg may help to increase the effectiveness of chemotherapy drugs by allowing them to work more effectively against cancer.
  
  Leucovorin Rescue Injection can help to improve the quality of life for cancer patients by reducing the side effects of chemotherapy and potentially increasing the effectiveness of cancer treatment.
  

Side Effects of Shilstine 50 mg Injection

• Like all medications, Shilstine Prefilled Syringe can cause side effects, but they do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
  

Most Common Side Effects of Shilstine 50 mg Injection

• • Nausea
  • Urticaria
  • Sleeplessness
  • Uneasiness
  • Fever
  • Redness
  • Abdominal pain
  • Diarrhoea
  • Vomiting
    

Common Side Effects of Shilstine 50 mg Injection

• • Breathing difficulty
  • Dizziness
  • Severe allergic reaction
  • Swelling all over the body
    

How to Use Shilstine 50 mg Injection?

• Shilstine 50 mg Injection is given intravenously (IV) or intramuscularly (IM) and administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of Leucovorin Rescue Injection will depend on the clinical condition of the patient's age and medical history and other factors. It is important to follow your doctor's instructions carefully when using this medication.
  

How Shilstine 50 mg Injection Works?

• Shilstine Prefilled Syringe also known as folinic acid. Shilstine Injection works by enhancing the effectiveness of certain chemotherapy drugs, such as 5-fluorouracil and methotrexate. Shilstine 50 mg helps to convert these chemotherapy drugs into their active form, which allows them to target and kill cancer cells.
  

Safety Advices Shilstine 50 mg Injection

Liver

Use with Caution

Shilstine 50 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Calcium Leucovorin 50 mg Injection and report any unusual symptoms or changes in liver function to their doctor. The dose of Calcium Leucovorin 50 mg Injection may need to be adjusted in patients with liver disease.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Shilstine Injection. Shilstine 50 mg may pass into breast milk and harm the infant. If you are breastfeeding and taking Shilstine Prefilled Syringe, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Shilstine Prefilled Syringe. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Pregnancy

Unsafe

Use of Shilstine 50 mg Injection may be unsafe during pregnancy, as animal studies indicate that it may harm the developing fetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Shilstine 50 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Driving

Safe

Shilstine 50 mg Injection is unlikely to affect your ability to drive or operate machinery. If you experience any side effects while taking Shilstine 50 mg, such as dizziness or drowsiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.

Kidney

Use with Caution

Patients with kidney disease should closely monitor kidney function while taking Shilstine 50 mg Injection and report any unusual symptoms or changes in kidney function to their physician. The dose of Calcium Leucovorin 50 mg Injection should be used with caution in patients with kidney disease. It is important to adjust the dose in patients with kidney disease.