


Calcium Folinate 50 mg Injection | 50 mg in 1 Vial

- Manufacturer/Marketed By
Samarth Life Sciences Pvt Ltd
- Active Pharmaceutical Ingredient
Calcium Leucovorin 50 mg
(Inclusive of all taxes)
Introduction of Calcium Folinate 50 mg Injection
Calcium Folinate 50 mg Injection is used to protect against the toxic effects of chemotherapy agents such as methotrexate and treat an overdose of anticancer medicines. Calcium Folinate Injection is used in the treatment of megaloblastic anemia due to folic acid deficiency when oral therapy is not possible. Calcium Leucovorin Injection 50 mg is also combined with 5-fluorouracil to treat advanced colorectal cancer. Calcium Folinate 50 mg should not be mixed with the same infusion as 5-fluorouracil because a precipitate may form.
This medicine may cause some adverse effects such as nausea, urticaria, sleeplessness, uneasiness, fever, redness, abdominal pain, diarrhea, and vomiting, which are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in the blood.
Before taking this medicine, you should inform us if you have any pre-existing diseases like seizures or liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To ensure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.
Calcium Folinate Injection is usually administered by a healthcare professional in a hospital or clinic setting. The exact dosing and schedule will be determined by the healthcare professional based on the patient's condition. It is important to follow the doctor's instructions for receiving Calcium Folinate 50 mg Vial and to report any side effects or concerns to the doctor.
Uses of Calcium Folinate 50 mg Injection
Leucovorin Rescue After High-Dose Methotrexate Therapy: Calcium Leucovorin Injection 50 mg is used to rescue or protect normal cells from the toxic effects of a high dose of methotrexate. It will reduce the risk of certain long-term side effects, such as liver damage and kidney damage.
Megaloblastic anemia: Anti-cancer Drug Calcium Folinate is used to treat megaloblastic anemia, a type of anemia with a lower than normal number of red blood cells, caused by a deficiency of folic acid, characterized by fatigue, shortness of breath, and pale skin.
Colorectal Cancer: Calcium Folinate 50 mg Injection is used to treat colorectal cancer, which is cancer that affects the colon or rectum.
Folic acid antagonist overdose: Calcium Folinate Injection diminishes the toxicity and counteracts the effects of overdosage of folic acid antagonists.
Benefits of Calcium Folinate 50 mg Injection
Anti-cancer Drug Calcium Folinate can reduce serious blood cell disorder symptoms like anemia, neutropenia, and thrombocytopenia, which occur as a side effect of some drugs like methotrexate, pyrimethamine, and trimethoprim.
Calcium Leucovorin Injection 50 mg can help to decrease the side effects of chemotherapy drugs, such as nausea, vomiting, and diarrhea, by protecting normal cells from the toxic effects of chemotherapy.
Calcium Folinate 50 mg may help to increase the effectiveness of chemotherapy drugs by allowing them to work more effectively against cancer.
Anti-cancer Drug Calcium Folinate can help to improve the quality of life for cancer patients by reducing the side effects of chemotherapy and potentially increasing the effectiveness of cancer treatment.
Side Effects of Calcium Folinate 50 mg Injection
Like all medications, Calcium Folinate 50 mg Vial can cause side effects, but they do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
Most Common Side Effects of Calcium Folinate 50 mg Injection
- Nausea
- Urticaria
- Sleeplessness
- Uneasiness
- Fever
- Redness
- Abdominal pain
- Diarrhoea
- Vomiting
Common Side Effects of Calcium Folinate 50 mg Injection
- Breathing difficulty
- Dizziness
- Severe allergic reaction
- Swelling all over the body
How to Use Calcium Folinate 50 mg Injection?
Calcium Folinate 50 mg Injection is given intravenously (IV) or intramuscularly (IM) and administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of Anti-cancer Drug Calcium Folinate will depend on the clinical condition of the patient's age and medical history and other factors. It is important to follow your doctor's instructions carefully when using this medication.
How Calcium Folinate 50 mg Injection Works?
Calcium Folinate 50 mg Vial also known as folinic acid. Calcium Folinate Injection works by enhancing the effectiveness of certain chemotherapy drugs, such as 5-fluorouracil and methotrexate. Calcium Folinate 50 mg helps to convert these chemotherapy drugs into their active form, which allows them to target and kill cancer cells.
Safety Advices Calcium Folinate 50 mg Injection

Liver
Use with Caution
Calcium Folinate 50 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Calcium Leucovorin Injection 50 mg and report any unusual symptoms or changes in liver function to their doctor. The dose of Calcium Leucovorin Injection 50 mg may need to be adjusted in patients with liver disease.

Breastfeeding
Unsafe
It is not recommended to breastfeed while taking Calcium Folinate Injection. Calcium Folinate 50 mg may pass into breast milk and harm the infant. If you are breastfeeding and taking Calcium Folinate 50 mg Vial, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Alcohol
Unsafe
It is generally not recommended to drink alcohol while taking Calcium Folinate 50 mg Vial. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Pregnancy
Unsafe
Use of Calcium Folinate 50 mg Injection may be unsafe during pregnancy, as animal studies indicate that it may harm the developing fetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Calcium Folinate 50 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Driving
Safe
Calcium Folinate 50 mg Injection is unlikely to affect your ability to drive or operate machinery. If you experience any side effects while taking Calcium Folinate 50 mg, such as dizziness or drowsiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.

Kidney
Use with Caution
Patients with kidney disease should closely monitor kidney function while taking Calcium Folinate 50 mg Injection and report any unusual symptoms or changes in kidney function to their physician. The dose of Calcium Leucovorin Injection 50 mg should be used with caution in patients with kidney disease. It is important to adjust the dose in patients with kidney disease.
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