Bharglob 16.5% Injection | 2 ml in 1 vial

Introduction of Bharglob 16.5% Injection

Bharglob 16.5% Injection is classified as an immunosuppressive drug which is prescribed for the treatment of immunoglobulin deficiency and certain inflammatory disorders. It is commonly used for individuals with primary immunodeficiency (present from birth) or secondary immunodeficiency (developed later in life) to treat immunoglobulin deficiency. Bharglob 16.5% Injection is also used in the treatment of inflammatory disorders such as primary immune thrombocytopenia (low platelet count), Guillain-Barre syndrome (temporary inflammation of the peripheral nerves leading to weakness in the legs and upper limbs), Kawasaki disease (inflammation of the blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of the peripheral nerves) and multifocal motor neuropathy (progressive weakness in the arms and legs).

Common side effects of Bharglob 16.5% Injection may include swelling or hardening of the injection site, headache, pain in the face, back, arms, legs, joints, or neck, fever, flu-like illness (runny nose and sore throat), blisters in the mouth and throat, and tightness in the throat. These side effects are usually temporary and will usually go away on their own. However, if they persist or get worse it is important to tell your doctor.

Bharglob 16.5% Injection should not be taken if you are allergic to any of the ingredients or if you have a blood clotting disorder. Before taking Bharglob Injection it is essential to inform your doctor about recent vaccinations or previous use of this product. Caution should be exercised when using Bharglob 16.5% Injection in individuals with immunoglobulin A (IgA) deficiency, an antibody that protects against infection. Although Bharglob 16.5% Injection is generally considered safe in children, and pregnant and breastfeeding women, caution should be exercised in the elderly. There is no known interaction between Bharglob Injection and alcohol. However, it is important to note that Bharglob Injection may cause dizziness, therefore it is recommended that you do not drive or operate heavy machinery if you experience dizziness.

Bharglob 16.5% Injection can be administered by either injection or infusion. Bharglob 16.5% Injection injection or infusion must be administered by a suitably trained healthcare professional as self-administration is not recommended. The injection is given subcutaneously, under the skin, and infusion is given intravenously, directly into a vein.

Uses of Bharglob 16.5% Injection

• Guillain Barre Syndrome
  
• Dermatomyositis
• Human Immunodeficiency Virus
• Immune thrombocytopenia
• Kawasaki Disease
• Multifocal Motor Neuropathy
• Stiff person Syndrome
• Multiple sclerosis
• Myasthenia Gravis
• Some Acute Infections
• Organ transplantation
• Pediatric HIV
• Autoimmune disease

Benefits of Bharglob 16.5% Injection

​Bharglob 16.5% Injection works by replacing the missing antibodies needed to fight infection and inflammation. It works in the same way as the body's own immunoglobulins. Immunoglobulins are a vital part of the immune system, responsible for recognizing antigens or foreign substances in the body and facilitating their elimination. Bharglob Injection is used to treat immunoglobulin deficiency in people with primary immunodeficiency (present from birth) and secondary immunodeficiency (developed later in life). It is also used to treat inflammatory disorders such as primary immune thrombocytopenia (low platelet count), Guillain-Barre syndrome (temporary inflammation of the peripheral nerves causing weakness in the legs and upper limbs), Kawasaki disease (inflammation of the blood vessels in children), chronic inflammatory demyelinating polyneuropathy or CIDP (long-term inflammation of the peripheral nerves) and multifocal motor neuropathy (progressive disease causing weakness in the arms and legs.​

Side Effects of Bharglob 16.5% Injection

​​​As with all medicines, Bharglob 16.5% Injection may have side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. Tell your doctor if they persist or if you're worried about them.​​​​

Most Common Side Effects of Bharglob 16.5% Injection

• Muscle cramps
  
• Joint pain
• Back pain
• Flushing
• Chills
• Nausea
• Vomiting
• Sensitivity to light

Common Side Effects of Bharglob 16.5% Injection

• Shortness of Breath
  
• Hypertension
• Fainting
• Irregular Heartbeats
• Extreme tiredness
• High Fever
• Anaphylaxis if allergic to IVIg.
• Brain Infection
• Lung problems
• ​Dizziness
• Sore throat
• Dark Urine
• Yellow Eyes and Skin
• Eye pain​

How to Use Bharglob 16.5% Injection?

​Bharglob 16.5% Injection should only be administered by a qualified healthcare professional. It is important to avoid self-administration. The injection is given subcutaneously, which means it is injected under the skin. The infusion is given intravenously, which means it is given directly into a vein.​

How Bharglob 16.5% Injection Works?

​Bharglob 16.5% Injection helps strengthen our immune system by providing the necessary antibodies to fight various infections. It also helps regulate immune system functions and reduces the likelihood of autoimmune disorders.​

Safety Advices Bharglob 16.5% Injection

Kidney

Use with Caution

Liver

Safe

Alcohol

Unsafe

Pregnancy

Unsafe

Breastfeeding

Unsafe

Driving

Unsafe

References

1. https://bsvgroup.com/assets/pdf/products/Bharglob.pdf 

2. https://www.fda.gov/media/119234/download 

3. https://www.intaspharma.com/wp-content/uploads/2021/12/Intaglob-2-ml-SC-PIL.pdf 

4. https://www.tga.gov.au/sites/default/files/auspar-human-normal-immunoglobulin-210621-pi.pdf