Cresemba 100 mg Capsule

Introduction of Cresemba 100 mg Capsule

Cresemba 100 mg Capsule is an azole antifungal medicine. It is used to treat fungal infections such as invasive aspergillosis and mucormycosis. Cresemba 100 mg Capsule works by killing the growth of the fungus in the body. The safety and efficacy of Cresemba 100 mg in children aged below 18 years have not yet been established.

This medicine may cause some common side effects including Hypokalaemia, Decreased appetite, Headache, Somnolence, Vomiting, Diarrhoea, Nausea, Abdominal pain, Chest pain, Fatigue, and Injection site reaction. These side effects usually disappear shortly after the injection. However, if they persist or bother you, you should inform your doctor or nurse. Call your doctor to help if you have signs of an allergic reaction to Cresemba (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling), or liver damage, low potassium levels in the body.

Cresemba 100 mg Capsule is not recommended in people suffering from a genetic heart rhythm disorder called short QT syndrome. If you are allergic to Cresemba 100 mg or any of these components. Suppose you are pregnant or have become pregnant. it is advised to consult a doctor before using Cresemba 100 mg. Avoid breastfeeding while taking Cresemba 100 mg Capsule. This medicine may cause drowsiness, confusion. or tiredness so be alert after taking Cresemba 100 mg. Avoid alcohol taking during the treatment it may increase the risk of liver damage. Additionally inform about any prescription and over-the-counter medicines, vitamins, or herbal supplements you take.

Cresemba 100 mg Capsule can be taken with or without food or as directed by your doctor. It is best to take the same time every day to improve the clinical condition. In case you miss a dose of Cresemba 100 mg take your next dose at your regularly scheduled time. The dose and length of treatment will depend on your condition. Do not stop taking this medicine without consulting your doctor.

Uses of Cresemba 100 mg Capsule

Invasive Aspergillosis: Cresemba 100 mg Capsule is used in the treatment of invasive aspergillosis a serious fungal infection caused by Aspergillus fungus. It occurs when the infection spreads from the lungs to the kidneys, brain, heart or skin. The symptoms include shortness of breath, fever, chest pain or cough (sometimes with blood).

Mucormycosis: Cresemba 100 mg Capsule is used in the treatment of mucormycosis, also known as zygomycosis, which is a rare but serious fungal infection caused by a group of fungi called micromycetes. Mucormycosis can affect different parts of the body, including the lungs, sinuses, brain, and skin. Symptoms depend on the affected area and may include fever, headache, nasal congestion, black discharge from the nose, facial swelling, chest pain, cough, skin lesions, and abdominal pain.

Benefits of Cresemba 100 mg Capsule

In this medicine isavuconazole is an active ingredient. It is a broad-spectrum antifungal medicine that is effective against a wide range of microorganisms. Cresemba 100 mg Capsule inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Cresemba 100 mg kills or stops the growth of the fungus.

Side Effects of Cresemba 100 mg Capsule

​​​​​​​Like all medication, Cresemba 100 mg Capsule may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​​

Most Common Side Effects of Cresemba 100 mg Capsule

• Diarrhoea
  
• Nausea 
• Abdominal pain 
• Chest pain
• Fatigue
  

Common Side Effects of Cresemba 100 mg Capsule

• Hypokalaemia 
• Decreased appetite 
• Headache 
• Somnolence 
• Vomiting

How to Use Cresemba 100 mg Capsule?

​​Cresemba 100 mg Capsule can be taken with or without food or as directed by your doctor. It is best to take the same time every day to improve the clinical condition. In case you miss a dose of Cresemba 100 mg take your next dose at your regularly scheduled time. The dose and length of treatment will depend on your condition. Do not stop taking this medicine without consulting your doctor.​

How Cresemba 100 mg Capsule Works?

Cresemba 100 mg Capsule contains the active ingredient isavuconazole, which is an antifungal medication. Cresemba 100 mg works by targeting the fungal cell membrane, specifically inhibiting an enzyme called lanosterol demethylase, which is responsible for the production of ergosterol - a key component of the fungal cell membrane. By inhibiting this enzyme, isavuconazole disrupts the integrity of the fungal cell membrane, leading to cell death and preventing the spread of the infection.

Safety Advices Cresemba 100 mg Capsule

Driving

Unsafe

Breastfeeding

Unsafe

Pregnancy

Unsafe

Alcohol

Unsafe

Liver

Safe

Kidney

Safe

References

1. Isavuconazole Capsule And Injection, Cresemba, Almac Pharma Services Limited, [date Of Revision July 2022], Product Leaflet

2. Cresemba- Isavuconazonium Sulfate Capsule, Daily Med.com, Avaliable Form

3. Summary Of Prescribing Information For Cresemba, (isavuconazole), Pfizer India, Avaliable Form

4. Cresemba 100 Mg Hard Capsules, Pfizer (thailand) Limited, Product Leaflet

5. Isavuconazole 100 Mg Capsule, Cdsco, Avaliable Form