Noxafil Tablet | 12 Tablets in 1 Strip

Introduction of Noxafil Tablet

Noxafil Tablet is used to prevent certain fungal infections in patients who have a severely weakened immune system (patients who have had chemotherapy) and belongs to a class of medicines called antifungals.  Noxafil 100 mg Tablet works by stopping the growth of fungi. This medicine is indicated for the prevention of invasive fungal infections in patients with neutropenia or haematopoietic stem cell transplant recipients receiving high-dose immunosuppressive therapy for graft-versus-host disease, and for the treatment of fungal infections.

Some common side effects of Noxafil Tablet include diarrhoea, nausea, fever, vomiting, headache, cough and low blood potassium. Most of these side effects of Noxafil 100 mg Tablet do not require medical attention and will gradually resolve over time, but if they persist or worsen, seek advice from your doctor.

Tell your doctor if you are allergic or hypersensitive to any of the ingredients in Noxafil Tablet, or if you are pregnant, suspect you may be pregnant, plan to become pregnant or are breastfeeding; your doctor will only prescribe Noxafil Tablet if the benefits outweigh the risks. Before taking this medicine, tell your doctor about your medical history and current therapies to rule out any possible adverse effects or interactions.

Noxafil Tablet is contraindicated in individuals with known hypersensitivity or allergy to other antifungal drugs such as ketoconazole, fluconazole, itraconazole or voriconazole. Before taking Noxafil Tablet it's necessary to consult your doctor if you have certain heart conditions such as abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhoea or vomiting while being treated with this medicine, it's important to tell your doctor immediately as these conditions may affect the medicine's ability to work.

Take Noxafil Tablet exactly as prescribed by your doctor. This medicine is usually taken by mouth with or without a full meal. Do not cut, crush, chunk or open this medicine. Your doctor will decide how much of this medicine to take and how long to keep taking it, based on your age, weight and medical condition. Do not stop taking your medicine unless your doctor or health care professional tells you.

Uses of Noxafil Tablet

• Fungal infections
• Prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.
  

Benefits of Noxafil Tablet

Noxafil Tablet is an antifungal drug contained in Posaconazol. It is used to treat fungal infections in adults. It is also indicated for the prevention of invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as haematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or patients with haematological malignancies with prolonged neutropenia from chemotherapy.

Side Effects of Noxafil Tablet

​Like any medication, Noxafil Tablet can have some side effects. You should tell your doctor or health care professional as soon as possible if you experience any of these side effects. Your doctor may be able to suggest ways to manage or reduce these side effects.​

Most Common Side Effects of Noxafil Tablet

• Itching
• Fever
• Diarrhoea
• Weakness
• Vomiting
• Heartburn
• Cough
• Sore throat
• Nose bleeds
• Increased sweating
• Sores on lips, mouth or throat
• Sleeplessness
• ​Swelling of hands
• Headache
• Chills
• Dizziness
• Constipation
• Backache
• Muscle pain
• Sore throat
  

Common Side Effects of Noxafil Tablet

• Yellowish skin and eyes
• Dark urine
• Arrhythmias ( irregular heartbeats)
• Sudden LOC ( loss of consciousness)
• Rapid or shortness of breathing
• Extreme tiredness
• Bleeding
• Neutropenia
• Hypokalemia ( low potassium level)
• Thrombocytopenia ( low platelets)
• Thrombophlebitis ( inflammation of a vein due to a blood clot)

How to Use Noxafil Tablet?

Follow your doctor's instructions exactly when taking Noxafil Tablet. It is usually taken by mouth with or without food. It is important not to change the shape of the medicine by cutting, crushing or opening. The dosage and duration of treatment will be determined by your doctor, taking into account factors such as your age, weight and medical condition. You mustn't stop taking this medicine unless your doctor or health care professional tells you to.

How Noxafil Tablet Works?

Noxafil Tablet inhibits the synthesis of ergosterol, a vital fungal cell membrane component. This disruption effectively treats fungal infections by weakening the membrane leading to cell death.

Safety Advices Noxafil Tablet

Pregnancy

Unsafe

Driving

Unsafe

Alcohol

Not known

Kidney

Use with Caution

Breastfeeding

Unsafe

Liver

Use with Caution

References

1. Posaconazole Modified Release Tablets, Product Leafle

​2. Posaconazole Gastro-resistant Tablets 100 Mg, Product Leaflet

3. Posaconazole Modified Release 100 Mg Tablets and 40 Mg/ml Oral Suspension, Product Leaflet

4. Posaconazole, Avaliable From

5. Posaconazole Tablet, Delayed Release, Avaliable From